Results 51 to 60 of about 5,551,543 (292)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

A Convenient Unified Model to Display the Mobile Keyhole-Mode Arc Welding Process

open access: yesApplied Sciences, 2020
Keyhole-mode plasma arc welding (PAW) has a good prospect in the manufacturing industry. Unified models of plasma arc and workpiece help to reveal the physical mechanism in PAW for a better application. Previous unified models either deal with a constant
Yan Li, Chen Su, Ling Wang, Chuansong Wu
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Numerical Study on the Phase Sensitivity Variation in Low Frequency Primary Microphone Calibrations

open access: yesApplied Sciences, 2020
The low frequency phase characteristics of microphones in a monitoring system are crucial for characterizing large-scale natural and artificial activities—e.g., earthquakes, nuclear explosions, or rocket launchings.
Fan Zhang   +4 more
doaj   +1 more source

Multi-physics simulations of automotive windscreen wipers

open access: yes
Multi-physics simulations of automotive windscreen ...
Bradley Graham (7386113)
core   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Recent Advances in Regulation Strategy and Catalytic Mechanism of Bi-Based Catalysts for CO2 Reduction Reaction

open access: yesNano-Micro Letters
Highlights Six major types of structural regulation strategies of various Bi-based catalysts used in photoelectrocatalytic CO2 reduction reaction (CO2RR) in recent years are comprehensively summarized.
Jianglong Liu   +7 more
doaj   +1 more source

Recent developments and discoveries in natural hazards mitigation research at the NHERI Lehigh Experimental Facility

open access: yesFrontiers in Built Environment
Natural hazards, including hurricanes and earthquakes, can escalate into catastrophic societal events due to the destruction of the built environment. To minimize the impact of such hazards on vulnerable communities, civil infrastructure must be designed
Liang Cao   +8 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

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