Results 91 to 100 of about 15,176,596 (284)

COMPUTING CONTINUOUS-TIME GROWTH MODELS WITH BOUNDARY CONDITIONS VIA WAVELETS [PDF]

This paper presents an algorithm for approximating the solution of deterministic/stochastic continuous-time growth models based on the Euler's equation and the transversality conditions.
Mercedes Esteban-Bravo, Jose M. Vidal-Sanz   +1 more
core   +2 more sources

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Positive solutions of second order multi-point boundary value problems with non-homogeneous boundary conditions [PDF]

Differential Equations & Applications, 2010
We are interested in the existence of positive solutions to multi-point boundary value problems for second order nonlinear differential equations with non-homogeneous boundary conditions. We show that results for the multi-point problems can be proved much in a similar way by methods available for the three point problem.
openaire   +1 more source

Axisymmetric compressive buckling of multi-walled carbon nanotubes under different boundary conditions [PDF]

, 2012
The paper studies the axisymmetric compressive buckling behavior of multi-walled carbon nanotubes (MWNTs) under different boundary conditions based on continuum mechanics model.
Sun, CQ, Chinese Acad Sci, Inst Mech, State Key Lab Nonlinear Mech, Beijing 100190, Peoples R China., Liu KX, Sun CQ(孙成奇), Hong YS(洪友士)   +4 more
core   +1 more source

Some new nonlinear second-order boundary value problems on an arbitrary domain

Advances in Difference Equations, 2018
In this paper, we develop the existence theory for nonlinear second-order ordinary differential equations equipped with new kinds of nonlocal non-separated type integral multi-point boundary conditions on an arbitrary domain. Existence results are proved
Ahmed Alsaedi, Mona Alsulami, Ravi P. Agarwal, Bashir Ahmad   +3 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

The effect of different combinations of boundary conditions on the average radiation efficiency of rectangular plates [PDF]

, 2014
The boundary conditions of a vibrating plate are known to have an influence on its sound radiation for frequencies below the critical frequency. To investigate this effect in a systematic way, the average radiation efficiency and radiated power are ...
Squicciarini, G., D. J. Thompson, Corradi, R., CORRADI, ROBERTO, Thompson, D.J., G. Squicciarini   +5 more
core   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source