Results 11 to 20 of about 144 (93)

Molecular Subtypes and Risk Prediction Model Based on Malignant Cell Differentiation Trajectories in Breast Cancer. [PDF]

open access: yesJ Cell Mol Med
ABSTRACT Breast cancer (BRCA) is characterised by complex cellular heterogeneity and differentiation hierarchies, which play a crucial role in bone metastasis and therapeutic resistance. However, existing classification systems remain inadequate in capturing these complexities, limiting their effectiveness in guiding treatment strategies.
Yan P   +11 more
europepmc   +2 more sources

PVT1 lincRNA signals an androgen‐dependent transcriptional activation program of oncogenes in prostate cancer cells

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Unraveling the networks that regulate androgen receptor (AR) function is critical to better understanding prostate cancer development and progression. Of particular interest in this regard is the long non‐coding RNA PVT1, which regulates gene expression in cancer and is upregulated in prostate tumors.
Maria Gabriela Berzoti‐Coelho   +7 more
wiley   +1 more source

Do Big Data Applications and Financial Innovation Lead to Enhanced Banking Performance? Evidence From the United Kingdom

open access: yesInternational Journal of Finance &Economics, EarlyView.
ABSTRACT Big data and financial innovations are vital to enhancing the performance of banking institutions. However, limited evidence exists on the effects of big data applications and financial innovation on bank performance. This study addresses this gap by constructing a theoretical framework linking big data applications and financial innovations ...
Mandella Osei‐Assibey Bonsu   +1 more
wiley   +1 more source

Policy success and failure in Australia

open access: yesAustralian Journal of Public Administration, EarlyView.
Abstract This paper introduces the seven articles in the symposium on policy success and failure together with a short introduction to the large literature on policy success and failure. The issue brings together an analysis of success and failure within seven discrete policy domains, including Indigenous policy; immigration; foreign policy; water ...
Keith Dowding   +2 more
wiley   +1 more source

Generative AI in Public‐Sector Retirement Plans: Behavioral Segmentation Beyond Demographics

open access: yesFINANCIAL PLANNING REVIEW, Volume 9, Issue 1, March 2026.
ABSTRACT Generative artificial intelligence (AI), exemplified by conversational tools such as ChatGPT, is rapidly reshaping financial advice delivery, yet its potential within employer‐sponsored retirement plans remains largely unexplored. This study examines the behavioral segments of public‐sector employees most likely to embrace generative AI tools ...
Eric T. Ludwig
wiley   +1 more source

Motorized DNAzymes Drive Enhanced Electrochemical Biosensing for Rapid Bacterial Detection

open access: yesSmall Methods, Volume 10, Issue 6, 24 March 2026.
The micromotor DNAzyme analyzer (Motolyzer) enables sensitive electrochemical detection of Legionella pneumophila proteins in unprocessed samples with high specificity. Upon target recognition, DNAzymes actively release redox barcodes, which are detected on DNA‐functionalized electrodes.
Amir Ali Akhlaghi   +9 more
wiley   +1 more source

The sensory penis: A comprehensive immunohistological and ontogenetic exploration of human penile innervation

open access: yesAndrology, Volume 14, Issue 3, Page 661-701, March 2026.
Abstract Background Penile sexual sensation relies on intricate neural structures that remain incompletely characterized. Immunohistological insights into their development and organization can enhance understanding of penile neuroanatomy and function, while optimizing surgical outcomes.
Alfonso Cepeda‐Emiliani   +6 more
wiley   +1 more source

Proteomic insights into the invasiveness and tumor progression of non‐functioning pituitary adenomas: A scoping review

open access: yesJournal of Neuroendocrinology, Volume 38, Issue 3, March 2026.
Abstract Nonfunctioning pituitary adenomas (NFPAs) are common intracranial tumors that, despite being histologically benign, can exhibit invasive growth, as well as postoperative tumor progression. Surgical resection is the primary treatment of choice; however, residual tumor tissue is frequently observed, with between 30% and 50% of these cases ...
Thomas Skoglund   +5 more
wiley   +1 more source

Human Skin‐Inspired Flexible Pressure Sensor with Multi‐Modulus Porous Structure

open access: yesAdvanced Electronic Materials, Volume 12, Issue 4, 18 February 2026.
Skin‐inspired dual‐modulus pressure sensor is developed by mimicking epidermis–dermis mechanics with a porous MWCNT/PDMS composite, achieving high sensitivity and wide linear range through simple fabrication, and enabling scalable, cost‐effective applications in wearable electronics, robotics, and human–machine interfaces.
Hyeongmin Park   +12 more
wiley   +1 more source

A multimodal deep learning framework for predicting sunitinib response in advanced clear cell renal cell carcinoma

open access: yesVIEW, Volume 7, Issue 1, February 2026.
In this study, we constructed a prognostic model for ccRCC patients treated with Sunitinib through a deep learning‐based multimodal approach. Our CGPR model further confirms the feasibility of integrating multimodal and provides guidance for future tumor patients to receive precision therapy.
Xi Tian   +11 more
wiley   +1 more source

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