Results 91 to 100 of about 1,245,641 (265)

Software Architectures: Multi-Scale Refinement

open access: yes2016 IEEE 14th International Conference on Software Engineering Research, Management and Applications (SERA), 2016
We propose a multi-scale modeling approach for complex software system architecture description. The multi-scale description may help to obtain meaningful granularities of these systems and to understand and master their complexity. This vision enables an architect designer to express constraints concerning different description levels, oriented to ...
Khlif, Ilhem   +3 more
openaire   +2 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

A Method for Improving Permeability Accuracy of Tight Sandstone Gas Reservoirs Based on Core Data and NMR Logs

open access: yesEnergies, 2019
Accurate calculation of the permeability of tight sandstone gas reservoirs has been a challenge, due to the enhanced effect of pore structure. Reservoir permeability with the same porosity and different pore structure often varies greatly.
Liang Liu   +3 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Low-frequency oscillations in narrow vibrated granular systems

open access: yesNew Journal of Physics, 2013
We present simulations and a theoretical treatment of vertically vibrated granular media. The systems considered are confined in narrow quasi-two-dimensional and quasi-one-dimensional (column) geometries, where the vertical extension of the container is ...
N Rivas, S Luding, A R Thornton
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Pioneering ML-driven framework for in-situ vertical surface roughness prediction in LPBF

open access: yesVirtual and Physical Prototyping
Real-time prediction of vertical surface roughness in laser powder bed fusion (LPBF) is essential for process control and quality assurance, yet it remains largely unexplored due to view-blocking by loose powder in the machine bed.
Sahar Toorandaz   +3 more
doaj   +1 more source

Classification of Complex Urban Fringe Land Cover Using Evidential Reasoning Based on Fuzzy Rough Set: A Case Study of Wuhan City

open access: yesRemote Sensing, 2016
Urban fringe is the transition zone fine grained with urban and non-urban land cover types. The complex landscape mosaic in this area challenges the land cover classification based on the remote-sensing data.
Yetao Yang, Yi Wang, Ke Wu, Xin Yu
doaj   +1 more source

Generalized multi-scale decision tables with multi-scale decision attributes

open access: yesInternational Journal of Approximate Reasoning, 2019
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Huang, Zhehuang   +3 more
openaire   +2 more sources

Homologous expression and purification of human HAX‐1 for structural studies

open access: yesFEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

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