Results 91 to 100 of about 1,245,641 (265)
Software Architectures: Multi-Scale Refinement
We propose a multi-scale modeling approach for complex software system architecture description. The multi-scale description may help to obtain meaningful granularities of these systems and to understand and master their complexity. This vision enables an architect designer to express constraints concerning different description levels, oriented to ...
Khlif, Ilhem +3 more
openaire +2 more sources
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Accurate calculation of the permeability of tight sandstone gas reservoirs has been a challenge, due to the enhanced effect of pore structure. Reservoir permeability with the same porosity and different pore structure often varies greatly.
Liang Liu +3 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Low-frequency oscillations in narrow vibrated granular systems
We present simulations and a theoretical treatment of vertically vibrated granular media. The systems considered are confined in narrow quasi-two-dimensional and quasi-one-dimensional (column) geometries, where the vertical extension of the container is ...
N Rivas, S Luding, A R Thornton
doaj +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Pioneering ML-driven framework for in-situ vertical surface roughness prediction in LPBF
Real-time prediction of vertical surface roughness in laser powder bed fusion (LPBF) is essential for process control and quality assurance, yet it remains largely unexplored due to view-blocking by loose powder in the machine bed.
Sahar Toorandaz +3 more
doaj +1 more source
Urban fringe is the transition zone fine grained with urban and non-urban land cover types. The complex landscape mosaic in this area challenges the land cover classification based on the remote-sensing data.
Yetao Yang, Yi Wang, Ke Wu, Xin Yu
doaj +1 more source
Generalized multi-scale decision tables with multi-scale decision attributes
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Huang, Zhehuang +3 more
openaire +2 more sources
Homologous expression and purification of human HAX‐1 for structural studies
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley +1 more source

