Results 81 to 90 of about 9,427,858 (262)

Balancing size and density segregation in bidisperse dense granular flows

open access: yesEPJ Web of Conferences, 2017
Several experimental studies have illustrated a balance between the segregation forces arising due to size- and density-differences. However, no detailed studies have been carried out to quantify this balance.
Tunuguntla Deepak R.   +1 more
doaj   +1 more source

Facile and Controllable Synthesis of Large-Area Monolayer WS2 Flakes Based on WO3 Precursor Drop-Casted Substrates by Chemical Vapor Deposition

open access: yesNanomaterials, 2019
Monolayer WS2 (Tungsten Disulfide) with a direct-energy gap and excellent photoluminescence quantum yield at room temperature shows potential applications in optoelectronics.
Biao Shi   +7 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Multi-scale 3-D Surface Description: Open and Closed Surfaces [PDF]

open access: yes, 1999
A novel technique for multi-scale smoothing of a free-form 3-D surface is presented. Complete triangulated models of 3-D objects are constructed automatically and using a local parametrization technique, are then smoothed using a 2-D Gaussian filter. Our
Yuen, P   +5 more
core  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

EPOS Multi-scale laboratories Data Services & Trans-national access program

open access: yes, 2020
EGU2020: Sharing Geoscience Online, 4-8 May, 2020EPOS (European Plate Observing System) is an ESFRI Landmark and European Research Infrastructure Consortium (ERIC).
Fernandez-Turiel, J. L.   +3 more
core   +1 more source

A Covalently Bonded Exchange Coupled Nanomagnet‐Based Hydrogel Composite for Microrobotic Applications

open access: yesAdvanced Intelligent Systems
The last decade has witnessed rapid progress in the development of soft microrobots for biomedical applications, largely powered by the incorporation of new materials in their design to address various challenges.
Lukas Hertle   +15 more
doaj   +1 more source

Low-frequency oscillations in narrow vibrated granular systems

open access: yesNew Journal of Physics, 2013
We present simulations and a theoretical treatment of vertically vibrated granular media. The systems considered are confined in narrow quasi-two-dimensional and quasi-one-dimensional (column) geometries, where the vertical extension of the container is ...
N Rivas, S Luding, A R Thornton
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Imaging, multi-scale and high contrast partial differential equations

open access: yes, 2016
This volume contains the proceedings of the Seoul ICM 2014 Satellite Conference on Imaging, Multi-scale and High-Contrast PDEs, held from August 7-9, 2014, in Daejeon ...
Sim, Imbo   +4 more
core   +1 more source

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