Results 91 to 100 of about 1,301,987 (287)
FEBS Open Bio, EarlyView.The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida +6 more
wiley +1 more source
Balancing size and density segregation in bidisperse dense granular flows
EPJ Web of Conferences, 2017 Several experimental studies have illustrated a balance between the segregation forces arising due to size- and density-differences. However, no detailed studies have been carried out to quantify this balance.
Tunuguntla Deepak R. +1 more
doaj +1 more source
Nanomaterials, 2019 Monolayer WS2 (Tungsten Disulfide) with a direct-energy gap and excellent photoluminescence quantum yield at room temperature shows potential applications in optoelectronics.
Biao Shi +7 more
doaj +1 more source
Software Architectures: Multi-Scale Refinement
2016 IEEE 14th International Conference on Software Engineering Research, Management and Applications (SERA), 2016 We propose a multi-scale modeling approach for complex software system architecture description. The multi-scale description may help to obtain meaningful granularities of these systems and to understand and master their complexity. This vision enables an architect designer to express constraints concerning different description levels, oriented to ...
Khlif, Ilhem +3 more
openaire +2 more sources
FEBS Open Bio, EarlyView.Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Low-frequency oscillations in narrow vibrated granular systems
New Journal of Physics, 2013 We present simulations and a theoretical treatment of vertically vibrated granular media. The systems considered are confined in narrow quasi-two-dimensional and quasi-one-dimensional (column) geometries, where the vertical extension of the container is ...
N Rivas, S Luding, A R Thornton
doaj +1 more source
Energies, 2019 Accurate calculation of the permeability of tight sandstone gas reservoirs has been a challenge, due to the enhanced effect of pore structure. Reservoir permeability with the same porosity and different pore structure often varies greatly.
Liang Liu +3 more
doaj +1 more source
Generalized multi-scale decision tables with multi-scale decision attributes
International Journal of Approximate Reasoning, 2019 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Huang, Zhehuang +3 more
openaire +2 more sources