Results 101 to 110 of about 1,301,987 (287)

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Pioneering ML-driven framework for in-situ vertical surface roughness prediction in LPBF

Virtual and Physical Prototyping
Real-time prediction of vertical surface roughness in laser powder bed fusion (LPBF) is essential for process control and quality assurance, yet it remains largely unexplored due to view-blocking by loose powder in the machine bed.
Sahar Toorandaz, Farima Liravi, Osazee Ero, Ehsan Toyserkani   +3 more
doaj   +1 more source

Multi-scaling and mesoscopic structures [PDF]

Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, 2010
Multi-scaling and the systematic investigation of mesoscopic structures represent a field of fruitful cooperation in physics, chemistry, mineralogy and life sciences. The increasing miniaturization of devices as well as the emphasis of recent research on microstructures with length scales of a few nanometres lead to paradigm changes that may impact not
openaire   +2 more sources

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

A Covalently Bonded Exchange Coupled Nanomagnet‐Based Hydrogel Composite for Microrobotic Applications

Advanced Intelligent Systems
The last decade has witnessed rapid progress in the development of soft microrobots for biomedical applications, largely powered by the incorporation of new materials in their design to address various challenges.
Lukas Hertle, Hyeon Ko, Valentin Gantenbein, Joaquin Llacer‐Wintle, Hao Ye, Mathieu Mirjolet, Andrea Veciana, Fabian C. Landers, Minsoo Kim, Elric Zhang, Minghan Hu, Josep Puigmartí‐Luis, Marta Estrader, Xiang‐Zhong Chen, Bradley J. Nelson, Salvador Pané   +15 more
doaj   +1 more source

Classification of Complex Urban Fringe Land Cover Using Evidential Reasoning Based on Fuzzy Rough Set: A Case Study of Wuhan City

Remote Sensing, 2016
Urban fringe is the transition zone fine grained with urban and non-urban land cover types. The complex landscape mosaic in this area challenges the land cover classification based on the remote-sensing data.
Yetao Yang, Yi Wang, Ke Wu, Xin Yu
doaj   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Soft magnetic microrobots with remote sensing and communication capabilities

Nature Communications
Remote communication in small-scale robotics offers a powerful way to enhance their capabilities, introducing options for state monitoring, multi-agent collaboration, and autonomous operation.
Quan Gao, Minsoo Kim, Denis von Arx, Elric Zhang, Xinzhi Zhang, Hao Ye, Christian Vogt, Claas Ehmke, Dianne Corsino, Federica Catania, Niko Münzenrieder, Michele Magno, Giuseppe Cantarella, Bradley J. Nelson, Salvador Pané   +14 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

An integrated fuzzy logic and machine learning platform for porosity detection using optical tomography imaging during laser powder bed fusion

International Journal of Extreme Manufacturing
Traditional methods such as mechanical testing and x-ray computed tomography (CT), for quality assessment in laser powder-bed fusion (LPBF), a class of additive manufacturing (AM), are resource-intensive and conducted post-production. Recent advancements
Osazee Ero, Katayoon Taherkhani, Yasmine Hemmati, Ehsan Toyserkani   +3 more
doaj   +1 more source