Results 61 to 70 of about 6,631,135 (316)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Teleoperated Magnetic Endoscopy: A Case Study and Perspective

open access: yesAdvanced Intelligent Systems
Teleoperated robotic surgery is a rapidly growing field that promises to overcome geographical barriers and share expertise over long distances for a variety of minimally invasive procedures.
Alexandre Mesot   +8 more
doaj   +1 more source

Multi-scale Hierarchical Segmentation [PDF]

open access: yesProcedings of the British Machine Vision Conference 1993, 1993
In the absence of a priori information on scales of interest vision systems should initially process in a scale invariant manner. The fact that any signal can only be sampled discretely further constrains the initial processing. The paper argues that a representation satisfying these requirements is an hierarchical segmentation of scalespace.
Lewis D. Griffin   +2 more
openaire   +1 more source

A multi-scale simulation of retinal physiology

open access: yesMathematical Biosciences, 2023
24 pages, 9 ...
Belal Abuelnasr, Adam R. Stinchcombe
openaire   +4 more sources

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Enhance the water oxidation performance of electrodeposited Ni(OH)2 through structure modulation by glutamic acid

open access: yesElectrochemistry Communications
Ni(OH)2 has been extensively studied as a promising electrocatalyst for the oxygen evolution reaction (OER). However, enhancing its OER properties is still required and challenging.
Wei Cui   +6 more
doaj   +1 more source

Application Integration Control System for Multi-Scale and Multi-PhysicsSimulation [PDF]

open access: yes, 2010
In the case of long-period and large-scale simulation, unexpected stop which is caused by execution time excess, outage of computers, outage of a network during file transfer and so on, become major issues.
SUZUKI, Yoshio   +7 more
core  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Ultrasound-mediated piezoelectric differentiation of neuron-like PC12 cells on PVDF membranes

open access: yesScientific Reports, 2017
Electrical and/or electromechanical stimulation has been shown to play a significant role in regenerating various functionalities in soft tissues, such as tendons, muscles, and nerves. In this work, we investigate the piezoelectric polymer polyvinylidene
Marcus Hoop   +8 more
doaj   +1 more source

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