Results 41 to 50 of about 1,301,987 (287)

MIdASv0.2.1 – MultI-scale bias AdjuStment

Geoscientific Model Development, 2022
Abstract. Bias adjustment is the practice of statistically transforming climate model data in order to reduce systematic deviations from a reference data set, typically some sort of observations. There are numerous proposed methodologies to perform the adjustments – ranging from simple scaling approaches to advanced multi-variate distribution-based ...
Peter Berg, Thomas Bosshard, Wei Yang, Klaus Zimmermann   +3 more
openaire   +4 more sources

Molecular insights for uranium(VI) adsorption at nano-TiO2 surfaces and reduction by alcohols and biomass sugars

Chemical Engineering Journal Advances, 2022
Titanium oxide (TiO2) plays a critical role for controlling uranium bioavailability, mobility and fate. Adsorption and reduction at nano-TiO2 surfaces represent two effective approaches for uranium remediation, while underlying mechanisms remain poorly ...
Qian Wang, Tingting Li, Chang Zhu, Xiaoxiao Huang, Gang Yang   +4 more
doaj   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

A-posteriori error estimates for the localized reduced basis multi-scale method

, 2014
We present a localized a-posteriori error estimate for the localized reduced basis multi-scale (LRBMS) method [Albrecht, Haasdonk, Kaulmann, Ohlberger (2012): The localized reduced basis multiscale method].
Ohlberger, Mario, Schindler, Felix
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Towards sustainable additive manufacturing: Enhanced productivity via numerical-experimental melt pool engineering in laser powder bed fusion of Ti-alloy

Journal of Materials Research and Technology
Laser Powder Bed Fusion (LPBF) offers a promising approach for creating metallic components with tailored properties. However, low production speed and high manufacturing costs remain challenges.
Mahyar Hasanabadi, Hamed Asgari, Nadia Azizi, Hamid Aghajani, Tatevik Minasyan, Ehsan Toyserkani   +5 more
doaj   +1 more source

Beyond Low Rank + Sparse: Multi-scale Low Rank Matrix Decomposition

, 2016
We present a natural generalization of the recent low rank + sparse matrix decomposition and consider the decomposition of matrices into components of multiple scales.
Lustig, Michael, Ong, Frank
core   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source