Results 181 to 190 of about 10,180,203 (304)

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source

Multi-Scale Modeling and Experimental Validation of Thermo-Mechanical Responses in Femtosecond Laser Micromachining of Copper. [PDF]

Materials (Basel)
Zhao J, Han X, Dong F, Liu S.
europepmc   +1 more source

Multi-scale modeling toolbox for single neuron and subcellular activity under Transcranial Magnetic Stimulation. [PDF]

Brain Stimul, 2021
Shirinpour S, Hananeia N, Rosado J, Tran H, Galanis C, Vlachos A, Jedlicka P, Queisser G, Opitz A.   +8 more
europepmc   +1 more source

Multi-scale models

Upstream and downstream multi-scale models of culture cells.
openaire   +1 more source

Electroencephalographic Normalization as a Biomarker of Clinical Recovery in Down Syndrome Regression Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Down syndrome regression disorder is a syndrome characterized by subacute loss of cognitive, behavioral, and functional abilities in individuals with Down syndrome. Electroencephalography abnormalities are frequently observed during evaluation, but it remains unclear whether these findings represent a dynamic marker of disease ...
Jonathan D. Santoro, Mackenzie Silverman, Maeve C. Lucas, Mariam M. Yousuf, Samuel T. Otey, Stella V. Gray, Brittany Jordan, Madeline D. Kahan, Latanya D. Agurs, Michelle Van Hirtum Das, Deborah Holder, Devin King, Eileen A. Quinn, Ryan Kammeyer, Michael S. Rafii   +14 more
wiley   +1 more source

Multi-scale modeling and sensitivity analysis for weak roadway areas: A case study of Xiaoyun coal mine. [PDF]

Sci Rep
Tian Z, Ma L, Liu Y, Xiao Z, Zhang Y, Li S.   +5 more
europepmc   +1 more source

Multi-scale modeling of intensive macroalgae cultivation and marine nitrogen sequestration. [PDF]

Commun Biol, 2021
Zollmann M, Rubinsky B, Liberzon A, Golberg A.   +3 more
europepmc   +1 more source

Blood RNA Biomarker Signatures for Early Diagnosis and Prognosis in Ischemic and Hemorrhagic Stroke: The IBIS‐CT1 Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau, Marie Bruguet, Irina Viakhireva‐Dovganyuk, François‐Mathias Merrien, Denis Marechal, Aurore Jourdain, Philippe Goas, Jordan Coris, Julien Asselineau, Maëlys Consigny, Gérald Le Gac, Serge Timsit   +11 more
wiley   +1 more source

Transfer learning based CEEMDAN-VMD secondary decomposition and multi-scale modeling for short-term electricity market price trend forecasting. [PDF]

Sci Rep
Zhang Y, Song X, Li C, Zhang Z, Zhang J.
europepmc   +1 more source

Correction: Hydrogen-activation mechanism of [Fe] hydrogenase revealed by multi-scale modeling. [PDF]

Chem Sci, 2021
Finkelmann AR, Senn HM, Reiher M.
europepmc   +1 more source