Results 51 to 60 of about 2,589,900 (302)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

An examination of quantitative methods for Forensic Signature Analysis and the admissibility of signature verification system as legal evidence. [PDF]

open access: yes, 2015
The experiments described in this thesis deal with handwriting characteristics which are involved in the production of forged and genuine signatures and complexity of signatures.
Chatzisterkotis, Thomas
core  

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Cryptanalysis of A New Multi-Proxy Multi-Signature Scheme

open access: yes, 2009
[[abstract]]Recently, Hwang and Chen [5] proposed a variation of proxy signature scheme called the multi-proxy multi-signature scheme. In their scheme, an authorized group of proxy signers is allowed to sign message on behalf of a group of original ...
孫宏民;謝濱燦;林宸堂
core  

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

A Non-repudiable Multi-Proxy Multi-Signature Scheme

open access: yes, 2012
[[abstract]]In this paper, we shall propose a threshold multi-proxy multi-signature scheme with shared verification. In the scheme allows the group of original signers to delegate the signing capability to the designated group of proxy signers ...
黃明祥;Hwang, Min-Shiang
core  

Adaptive feature thresholding for off-line signature verification

open access: yes, 2008
This paper introduces Adaptive Feature Thresholding (AFT) which is a novel method of person-dependent off-line signature verification. AFT enhances how a simple image feature of a signature is converted to a binary feature vector by significantly ...
Larkins, Robert L.   +3 more
core   +1 more source

An Improved RSA-based Certificateless Multi-signature Scheme

open access: yes工程科学与技术, 2017
:Three forgery attacks on Liu Li et al.'s RSA-based certificateless multi-signature scheme were first presented.It could be found that their scheme was vulnerable to key replacement attacks.The scheme also could not resist conspiracy attack of dishonest ...
农强, 黄茹芬, 陈群山
doaj  

Multi-signature based person re-identification

open access: yesElectronics Letters, 2012
A novel appearance-based method for person re-identification is proposed. The approach exploits three local features to extract the shape and the chromatic appearance of an individual. Robustness against low resolution images, viewpoint and illumination changes, occlusions and pose variations is achieved by a novel signature.
MARTINEL, Niki, FORESTI, Gian Luca
openaire   +2 more sources

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