Results 101 to 110 of about 4,342,726 (293)

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

The effect of the active carbonyl groups and residual acid on the ammonia adsorption over the acid-modified activated carbon

Frontiers in Environmental Science, 2023
Changming Li, Shuying Zhao, Shuying Zhao, Ming Li, Zhiliang Yao, Yang Li, Chuanqiang Zhu, Si-Min Xu, Junjie Li, Jian Yu   +9 more
doaj   +1 more source

Research on a Miniature Underwater Vehicle Based on a Multi-Unit Underwater Coupled Jet Drive

Actuators
The underwater unstructured environment poses new challenges for the miniaturization and flexibility of underwater vehicles. This paper proposes a method of using micrometer-scale vibrations of piezoelectric vibrators to drive macroscopic jets.
Dong Zhang, Xingming Ma, Xue Zhang, Peng Gao, Kai Li   +4 more
doaj   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Strengthened ENSO Amplitude Contributed to Regime Shift in the Hadley Circulation

Geophysical Research Letters
Understanding the variability in the Hadley circulation (HC) changes is crucial for understanding ocean‐atmosphere interactions. In this study, the variability in the boreal winter HC in the last 4 decades is explored using multiple reanalyzes and model ...
Juan Feng, Shuang Wang, Jianping Li
doaj   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

A dual context-aware basecaller for nanopore direct RNA sequencing

Nature Communications
Nanopore direct RNA sequencing (DRS) offers distinct advantages for transcriptome analysis over the traditional high-throughput RNA sequencing methods by preserving native RNA modifications, eliminating polymerase chain reaction bias, and simplifying the
Shaohui Xie, Lulu Ding, Yang Yu, Ling Liu, Yiwen Sun, Jianqiang Li, Jue Ruan, Zexuan Zhu   +7 more
doaj   +1 more source

On Ship Systems Multi-state Safety Analysis [PDF]

TransNav, 2007
A multi-state approach to defining basic notions of the system safety analysis is proposed. A system safety function and a system risk function are defined.
Przemyslaw Dziula, Miroslaw Jurdzinski, Krzysztof Kolowrocki, Joanna Soszynska   +3 more
doaj  

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Major challenges and recent advances in characterizing biomass thermochemical reactions

Resources Chemicals and Materials
Thermochemical conversions are pathways for biomass utilization to produce various value-added energy and chemical products. For the development of novel thermochemical conversion technologies, an accurate understanding of the reaction performance and ...
Zhennan Han, Junrong Yue, Xi Zeng, Jian Yu, Fang Wang, Yu Guan, Xuejing Liu, Fu Ding, Liangliang Fu, Xin Jia, Xingfei Song, Chao Wang, Yanbin Cui, Lei Shi, Kangjun Wang, Vladimir Zivkovic, Dingrong Bai, Guangwen Xu   +17 more
doaj   +1 more source