Results 71 to 80 of about 134,390 (294)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

One-Pass Incomplete Multi-View Clustering [PDF]

open access: yes, 2019
Real data are often with multiple modalities or from multiple heterogeneous sources, thus forming so-called multi-view data, which receives more and more attentions in machine learning. Multi-view clustering (MVC) becomes its important paradigm.
Chen, Songcan, Hu, Menglei
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Multi-agent Behaviour Segmentation via Spectral Clustering [PDF]

open access: yes, 2007
18.02.14 KB. OK to add accepted version to spiral, AAAI permits.We examine the application of spectral clustering for breaking up the behaviour of a multi-agent system in space and time into smaller, independent elements.
Takács, B, Demiris, Y, Butler, S
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Robust vector-weighted and matrix-weighted multi-view hard c-means clustering

open access: yesIntelligent Systems with Applications
With the rapid advancement of information technology, multi-view data has become ubiquitous, prompting extensive attention towards multi-view clustering algorithms.
Zhe Liu   +6 more
doaj   +1 more source

Robust Auto-weighted Multi-view Subspace Clustering

open access: yesJisuanji kexue yu tansuo, 2021
As the ability to collect and store data improving, real data are usually made up of different forms (view). Therefore, multi-view learning plays a more and more important role in the field of machine learning and pattern recognition.
FAN Ruidong, HOU Chenping
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Spectral clustering with distinction and consensus learning on multiple views data.

open access: yesPLoS ONE, 2018
Since multi-view data are available in many real-world clustering problems, multi-view clustering has received considerable attention in recent years. Most existing multi-view clustering methods learn consensus clustering results but do not make full use
Peng Zhou, Fan Ye, Liang Du
doaj   +1 more source

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