Results 121 to 130 of about 14,284 (299)

“Membrane‐Guided” Repair Strategy: Precision Delivery of GGT1 Degrader for Targeted Repair and Regeneration of Spinal Cord Neurons

Advanced Science, EarlyView.
This study confirms that GGT1 is a key driver of neuronal ferroptosis following spinal cord injury. We developed NSCm@EA, a biomimetic delivery system coated with neural stem cell membranes, for precise delivery of enocyanin to injured neurons. By combining targeted delivery with ubiquitination degradation mechanisms, this system promotes MGRN1 ...
Tao Yang, Lei Ye, Peigen Xie, Tao Song, Jian Chen, Heng Zhao, Zhengshan Liu, Xi Chen, Jianing Ding, Xintian Ding, Ao Shao, Miaomiao Wu, Fengdong Zhao, Siyue Tao, Tao You   +14 more
wiley   +1 more source

Targeting Golgi–STING Signaling to Reprogram Innate and Adaptive Immunity for the Treatment of Implant‐Associated Infections

Advanced Science, EarlyView.
This study presents an ultrasound‐responsive nanoplatform, CS‐BT@MZ@NEs, with a BaTiO3/Mn‐Zif‐8 core and a chondroitin sulfate coating for Golgi targeting. By leveraging neutrophil hitchhiking, it enables targeted delivery to infection sites. Under ultrasound stimulation, CS‐BT@MZ@NEs generates ROS and modulates Golgi pH to activate cGAS–STING ...
Shicheng Huo, Naifeng Zhu, Zhuocheng Lyu, Yifei Liu, Zhenjiang Xu, Chun Zhou, Yaochao Zhao, Changgui Shi   +7 more
wiley   +1 more source

A Connectionist and Multivariate Approach to Science Maps: Som, Clustering and Mds Applied to Library & Information Science Research. [PDF]

, 2006
The visualization of scientific field structures is a classic of scientometric studies. This paper presents a domain analysis of the library and information science discipline based on author co-citation analysis (ACA) and journal cocitation analysis ...
De-Moya-Anegón, Félix, Jiménez-Contreras, E., Herrero-Solana, Víctor   +2 more
core  

Compact Tabletop Magnetic Resonance Elastography for Mapping Soft Tissue Viscoelasticity

Advanced Science, EarlyView.
This work introduces a compact, low‐cost tabletop magnetic resonance elastography platform for high‐resolution viscoelastic mapping in soft‐tissue specimens. Using this method in human colorectal liver metastases, we demonstrate fully automated biomechanical profiling of treatment response and show that heterogeneity‐based metrics outperform ...
Weijie Zhao, Lisa‐Marie Skrip, Heiko Tzschätzsch, Tom Meyer, Hossein S. Aghamiry, Alexander Arnold, Lene Änne Böhne, Jakob Jordan, Oliver Boehm, Agnes K. Boehm, Steffen Görner, Jakob Schattenfroh, Yanglei Wu, Pedro Augusto Dantas de Moraes, Johann Pratschke, Jürgen Braun, Igor M. Sauer, Jing Guo, Ingolf Sack, Karl H. Hillebrandt   +19 more
wiley   +1 more source

Nonmetric multidimensional scaling (MDS) showing ordination of the microbiome communities associated with cigarette beetle across phases.

Nonmetric multidimensional scaling (MDS) showing ordination of the microbiome communities associated with cigarette beetle across phases.
Paul X. Clinton (17817269), Thanga Suja Srinivasan (17817263), Krishnamanikumar Premachandran (17817266)   +2 more
core   +1 more source

Neuromorphic Near‐Sensor and In‐Sensor Computing Enabled by Next‐Generation Material‐Based Sensors

Advanced Science, EarlyView.
This Review presents a structural framework that classifies neuromorphic sensing into near‐sensor and in‐sensor architectures, clarifying physical coupling between sensing and computation. The framework connects neural and synaptic device functions with recent advances in optical, mechanical, and chemical sensing, compares energy consumption and ...
Su Yeon Jung, Gwang Ya Kim, Sejin Kim, Hyunjong Seo, Se Gi Lee, Sang Min Won, Dongjoon Rhee, Joohoon Kang   +7 more
wiley   +1 more source

Sustainability of Packaged UHT Cow’s Milk Products Using the Multidimensional Scaling (MDS) Method

Buletin Peternakan
Product positioning is how a product is defined by consumers in terms of the attributes of competitors or the place where the product is distinguished in the minds of consumers compared to other products. This study aims to analyze the sustainability of packaged UHT cow's milk products in the market using the Multidimensional Scaling (MDS) non-metrik ...
Astati Astati, Amriana Hifizah, Anas Qurniawan   +2 more
openaire   +2 more sources

NIR‐II‐Trackable LYTACs Phyto‐Nanotheranostics for Source‐Microenvironment Dual‐Track ROS Regulation in Acute Gouty Arthritis

Advanced Science, EarlyView.
The TPR‐LYTACs nanomaterial offers a dual‐pathway strategy for precise gouty arthritis treatment by targeting and degrading the ROS‐producing enzyme NOX2 inside macrophages while its antioxidant core clears accumulated ROS outside. This “source inhibition and microenvironment scavenging” approach, guided by NIR‐II imaging, effectively controls local ...
Jian Zhang, Yingying Wang, Lujie Yu, Chunmei Jiang, Haoyu Liu, Yaohua Chen, Shutong Wu, Qin Liu, Lingling Wei, Xiaochun Zheng, Huifang Hao, Mengting Gao, Weiwei Kang, Rong Dai, Ziliang Zheng, Ruiping Zhang   +15 more
wiley   +1 more source

Multidimensional Scaling with Regional Restrictions for Facet Theory: An Application to Levi's Political Protest Data

Multidimensional scaling (MDS) is often used for the analysis of correlation matrices of items generated by a facet theory design. The emphasis of the analysis is on regional hypotheses on the location of the items in the MDS solution.
Groenen, P.J.F., Lans, A. van der
core  

Perceptual map from Multidimensional Scaling (MDS) from similarity matrix obtained from napping experiments (Tucker’s coefficient of congruence = 0.984).

, 2019
Perceptual map from Multidimensional Scaling (MDS) from similarity matrix obtained from napping experiments (Tucker’s coefficient of congruence = 0.984).
Christopher T. Simons (252353), Julie Peterson (1664275), Devin G. Peterson (2847980), Ashley Soldavini (7460387), Laurianne Paravisini (7460384)   +4 more
core   +1 more source