Results 121 to 130 of about 234,319 (307)
Advanced Science, EarlyView.This study identifies C4 as a lead inhibitor of the Lpt system. Notably, C4 potentiates colistin activity by disrupting LPS transport and remodeling phospholipid homeostasis, revealing a functional interplay between the Lpt and Mla systems. These findings establish a mechanistic link between Lpt inhibition and membrane lipid remodeling, positioning Lpt–
Jianya Luo +6 more
wiley +1 more source
Frontiers in AntibioticsMultidrug-resistant organisms are bacteria that are no longer controlled or killed by specific drugs. One of two methods causes bacteria multidrug resistance (MDR); first, these bacteria may disguise multiple cell genes coding for drug resistance to a ...
Muhammad Naveed +6 more
doaj +1 more source
Characterisation and modulation of drug resistance in lung cancer cell lines [PDF]
, 2010 Chemotherapy drug resistance is a major obstacle in the treatment of cancer. It can result from an increase in levels of cellular drug efflux pumps such as P-glycoprotein (P-gp).
Dunne, Gráinne
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Guidelines for Detecting the Foodborne Antibiotic‐Resistant Bacteria
AgriFood: Journal of Agricultural Products for Food, EarlyView.ABSTRACT Foodborne antibiotic‐resistant bacteria threaten global public health and the economic. Standardized detection methods are crucial for effective prevention and control. Researchers encounter difficulties in choosing suitable techniques due to the variety of available approaches and the intricate nature of resistance mechanisms.
Yuanye Zeng, Fengxia Yang
wiley +1 more source
BMC Infectious DiseasesBackground Pseudomonas aeruginosa is one of the leading causes of nosocomial infections and the most common multidrug-resistant pathogen. This study aimed to determine antimicrobial resistance patterns, biofilm-forming capacity, and associated factors of
Matifan Dereje Olana +2 more
doaj +1 more source
, 2019 Heba Shehta Said, Eman Salama Abdelmegeed Department of Microbiology and Immunology, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt Introduction: Enterococci commonly inhabit the gastrointestinal tract of both human and animals; however,
Said HS, Abdelmegeed ES
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The Role of the Gut Microbiota in Allogeneic Hematopoietic Cell Transplantation
American Journal of Hematology, EarlyView.ABSTRACT Allogeneic hematopoietic cell transplantation (allo‐HCT) is an effective treatment for patients with high‐risk hematologic malignancies. Over the last decade, gut microbiota composition during allo‐HCT has been associated with patients' outcomes.
Wenjing Hao +4 more
wiley +1 more source
Role of Multidrug Resistance Associated Proteins in Drug Development
, 2012 The Multidrug Resistance Associated Proteins ((MRP1, MRP2, MRP3, MRP4, MRP5, MRP6, MRP7, MRP8 and MRP9) belong to the ATP-binding cassette superfamily (ABCC family) of transporters expressed differentially in the liver, kidney, intestine and blood-brain ...
Liu, Jun-Ping +3 more
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Resistance to antimicrobial agents in bifidobacteria
, 2005 Includes bibliographical references (leaves 95-106).For bifidobacteria to survive and achieve colonisation, they have to interact with inhibitory host-produced substances such as bile salts.
Price, Claire Emile
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Immunosuppressive drug interactions and resistance in mononuclear cells from renal transplant patients [PDF]
Existing anti-rejection drug regimes are inadequate since patients receive drugs despite serious side effects and poor response. New drugs are being developed which ultimately may allow for prescribing of rational, patient-specific immunosuppressive ...
Delaney, Michael Paul
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