Results 301 to 310 of about 365,495 (322)
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Multidrug-resistant tuberculosis
Nature Reviews Disease PrimersTuberculosis (TB) remains the foremost cause of death by an infectious disease globally. Multidrug-resistant or rifampicin-resistant TB (MDR/RR-TB; resistance to rifampicin and isoniazid, or rifampicin alone) is a burgeoning public health challenge in several parts of the world, and especially Eastern Europe, Russia, Asia and sub-Saharan Africa.
Keertan Dheda +11 more
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Der Urologe A, 1996
The past decade has seen the successful application of genetic techniques in the dissection of the most important phenotypes of cancer cells. In the case of drug resistance mechanisms, the elucidation of the genes involved in resistance to anticancer agents has led to new and unexpected information about tumor physiology and may well open therapeutic ...
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The past decade has seen the successful application of genetic techniques in the dissection of the most important phenotypes of cancer cells. In the case of drug resistance mechanisms, the elucidation of the genes involved in resistance to anticancer agents has led to new and unexpected information about tumor physiology and may well open therapeutic ...
openaire +2 more sources
Multidrug-resistant tuberculosis
Infectious Disease Clinics of North America, 2002Multidrug-resistant TB is a growing public health problem. Although control of the multidrug-resistant TB epidemic has been achieved in New York City, strains of multidrug-resistant TB are found in nearly every state. Much of the world faces a growing problem with no immediate solution.
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Multidrug-Resistance Transporters
2002P-glycoprotein was initially isolated due to its role in multidrug resistance to cancer chemotherapeutics. Recent work, however, makes it increasingly apparent that this transporter is also involved in the pharmacokinetics of many drugs. P-gp is strategically expressed in the luminal epithelial cells of organs often associated with drug absorption and ...
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Cancer chemotherapy and biological response modifiers, 1990
The understanding of the mechanism(s) of multidrug resistance has increased at a rapid rate over the past year. Many new inhibitors, new agents equitoxic to MDR and sensitive cells, techniques for screening, and application to therapies will no doubt be within the grasp of the clinical oncologist over the next few years.
R L, Fine, B A, Chabner
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The understanding of the mechanism(s) of multidrug resistance has increased at a rapid rate over the past year. Many new inhibitors, new agents equitoxic to MDR and sensitive cells, techniques for screening, and application to therapies will no doubt be within the grasp of the clinical oncologist over the next few years.
R L, Fine, B A, Chabner
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Cancer surveys, 1987
Multidrug resistance describes a complex phenotype whose predominant feature is resistance to a wide range of structurally unrelated cytotoxic compounds, many of which are anticancer agents. This phenotype occurs frequently in mammalian cell lines and transplantable tumours selected for resistance to a single drug.
J H, Gerlach +3 more
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Multidrug resistance describes a complex phenotype whose predominant feature is resistance to a wide range of structurally unrelated cytotoxic compounds, many of which are anticancer agents. This phenotype occurs frequently in mammalian cell lines and transplantable tumours selected for resistance to a single drug.
J H, Gerlach +3 more
openaire +1 more source