Results 51 to 60 of about 18,450 (254)

miR-669a-5p promotes adipogenic differentiation and induces browning in preadipocytes

Adipocyte, 2022
Obesity is a major global health issue that contributes to the occurrence of metabolic disorders. Based on this fact, understanding the underlying mechanisms and to uncover promising therapeutic approaches for obesity have attracted intense investigation.
Xiaoqiong Tan, Tingting Zhu, Linqiang Zhang, Lin Fu, Ying Hu, Huiqin Li, Chengbin Li, Jingjing Zhang, Bin Liang, Jing Liu   +9 more
doaj   +1 more source

Engineering of Metabolic Pathways by Artificial Enzyme Channels. [PDF]

, 2015
Application of industrial enzymes for production of valuable chemical compounds has greatly benefited from recent developments in Systems and Synthetic Biology.
Boccaccini, AR, Detsch, R, Pröschel, M, Sonnewald, U   +3 more
core   +3 more sources

The glycine decarboxylase complex multienzyme family in Populus [PDF]

Journal of Experimental Botany, 2007
In plants, the glycine decarboxylase complex (GDC) cooperates with serine hydroxymethyltransferase (SHMT) to mediate photorespiratory glycine-serine interconversion. GDC is also postulated to be an integral component of one-carbon (C1) metabolism in heterotrophic tissues, although molecular evidence in plants is scarce.
Mohan, Rajinikanth, Scott A, Harding, Chung-Jui, Tsai   +2 more
openaire   +2 more sources

Gallium‐Doped MXene Nanozymes Protect Liver Through Multi‐Death Pathway Blockade and Hepatocyte Regeneration

Advanced Science, EarlyView.
This study develops gallium‐doped V2C MXene nanozymes (Ga‐V2C) to treat acetaminophen‐induced liver injury through multi‐death pathway blockade and hepatocyte regeneration. Unlike conventional single‐target therapies like N‐acetylcysteine, Ga‐V2C nanozymes enable oxidative stress suppression, apoptosis, and ferroptosis inhibition, and enhanced ...
Xiaopeng Cai, Jingwen Deng, Liqing Wang, Junjie Su, Dongyi Xian, Yilang Yan, Xinyu Yang, Chuanbin Wu, Tingting Peng, Yuan Ding, Guilan Quan, Weilin Wang, Min Zhou, Chao Lu   +13 more
wiley   +1 more source

Assembly of Cellulases from Separate Catalytic Domains and a Cellulose-Binding Module for Understanding Cooperative Crystalline Cellulose Degradation

Applied Sciences
The biochemical degradation of abundant cellulosic biomass for industrial use and energy production has been extensively researched in recent years. Some elaborate cellulose digestion approaches have been developed based on specialized bacteria, which ...
Katharina K. I. Schmitt, Hidehiko Hirakawa   +1 more
doaj   +1 more source

Immune response of broilers fed conventional and alternative diets containing multi-enzyme complex

Brazilian Journal of Poultry Science, 2013
The present study aimed at evaluating the effect of adding a commercial multi-enzyme complex to conventional and alternative broiler diets on the immune response and occurrence of lesions in the intestinal mucosa.
R Montanhini Neto, ML Ceccantini, JIM Fernandes   +2 more
doaj   +1 more source

Sulfite: Cytochrome \u3cem\u3ec\u3c/em\u3e Oxidoreductase from \u3cem\u3eThiobacillus novellus\u3c/em\u3e [PDF]

, 2000
Direct oxidation of sulfite to sulfate occurs in various photo- and chemotrophic sulfur oxidizing microorganisms as the final step in the oxidation of reduced sulfur compounds and is catalyzed by sulfite:cytochrome c oxidoreductase (EC1.8.2.1).
Bennett, Brian, Dahl, Christiane, Deutzmann, Rainer, Kappler, Ulrike, McEwan, Alistair G., Rethmeier, Jörg, Schwarz, Günter   +6 more
core   +1 more source

NIR‐Activatable Domino Cascade Catalysis Nanozyme Reactor for Multi‐Mechanism Synergistic Immunotherapy in Bladder Cancer

Advanced Science, EarlyView.
This study presents an intravesical delivery strategy of ferroptosis‐ and immunity‐inducing nanozyme‐loaded thermoresponsive hydrogels (FMCC@PNH) for enhanced bladder cancer therapy. Abstract Current intravesical therapies for bladder cancer after resection are limited by poor tissue penetration, off‐target effects, and insufficient efficacy.
Yongnan Jiang, Qingling Zhang, Yuhan Zhang, Xinlu Yu, Bo Jia, Yulong Dong, Yalong Wu, Kelong Fan, Xinquan Gu, Lei Ji, Wei Jiang, Bin Liu   +11 more
wiley   +1 more source

Multienzyme complexes of eukaryotic aminoacyl-tRNA synthetases

Bioscience Reports, 1983
The high-molecular-mass aminoacyl-tRNA synthetase complexes in higher eukaryotes are discrete non-artifactual multienzyme complexes of similar composition which can be purified from different tissues of different species by different techniques. These high-Mr complexes are composed of synthetases in simple stoichiometric ratios.
C V, Dang, C V, Dang
openaire   +2 more sources

Photocatalytically Activated Cu‐N1S3 Single‐Atom Nanozyme: Enhancing Enzyme Activities and Antibacterial Synergy for Highly Efficient Fruit Preservation

Advanced Science, EarlyView.
This study presents S‐coordinated Cu single‐atom nanozymes (Cu/CNS) fabricated via mild photocatalytic self‐assembly strategy. The nanozyme exhibits exceptional multi‐enzyme activity and near‐perfect antimicrobial efficacy. Incorporated into chitosan‐gelatin film, it enables pH‐responsive, broad‐spectrum fruit preservation, more than doubling the shelf‐
Chuanlong Men, Chenchen Wu, Lei Wang, Shengjie Gao, Yu Mao, Wei Liu, Changhong Liu, Lei Zheng   +7 more
wiley   +1 more source