Immunological and biosynthetic studies on the mammalian 2‐oxoglutarate dehydrogenase multienzyme complex [PDF]
Anne Hunter, J. Gordon Lindsay
openalex +1 more source
Advanced Therapeutic Approach Based on LDHs–Mimetic Oxidoreductase
Overview of Sructure, Multienzyme‐mimicking Activity and Advanced Therapeutic Approach Based on LDHs–Mimetic Oxidoreductase. Abstract Redox dysregulation is recognized as a key driver in the pathophysiology of numerous refractory diseases, contributing significantly to the progression and poor prognosis.
Kai Song +9 more
wiley +1 more source
Physiological Evidence for Isopotential Tunneling in the Electron Transport Chain of Methane-Producing Archaea [PDF]
Many, but not all, organisms use quinones to conserve energy in their electron transport chains. Fermentative bacteria and methane-producing archaea (methanogens) do not produce quinones but have devised other ways to generate ATP. Methanophenazine (MPh)
Buan, Nicole R., Duszenko, Nikolas
core +1 more source
Repression of the auxin response pathway increases Arabidopsis susceptibility to necrotrophic fungi
In plants, resistance to necrotrophic pathogens depends on the interplay between different hormone systems, such as those regulated by salicylic acid (SA), jasmonic acid (JA), ethylene, and abscisic acid.
AbuQamar +65 more
core +1 more source
Reticular Chemistry: A Versatile Platform for Engineering Heterogenous Biocatalysts
Rational design of reticular‐based heterogeneous biocatalysts enables significant enhancement in enzyme activity recovery and even achieves catalytic performance beyond native enzymes. Abstract Reticular materials, including metal‐organic frameworks (MOFs), covalent organic frameworks (COFs), and hydrogen‐bonded organic frameworks (HOFs), have emerged ...
Si Liu +6 more
wiley +1 more source
Investigations in space-related molecular biology, including considerations of the molecular organization of extraterrestrial matter Technical progress report [PDF]
Space related molecular biology and molecular organization of extraterrestrial matter - design and construction of high vacuum container for transfer of extraterrestrial collecting ...
Fernandez-Moran, H.
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Purification and characterization of recombinant pyruvate dehydrogenase kinases from pea and soybean plants [abstract] [PDF]
only availableFaculty Mentor: Dr. Douglas Randall, BiochemistryThe pyruvate dehydrogenase complex (PDC) is a large multienzyme complex catalyzing the oxidative decarboxylation of pyruvate and concomitant reduction of NAD to yield acetyl-CoA and NADH ...
Hoyos, Elizabeth +3 more
core
This review introduces the development and classification of all‐nanozyme cascade reaction systems, highlighting mechanistic insights and research methods for understanding catalytic features and design principles. It provides detailed classifications, surveys recent applications in biosensing and therapy, and discusses the challenges that all‐nanozyme
Caixia Zhu +4 more
wiley +1 more source
Interferon y Stimulation Modulates the Proteolytic Activity and Cleavage Site Preference of 20S Mouse Proteasomes [PDF]
The proteasome is a 700-kD multisubunit enzyme complex with several proteolytically active sites. The enzyme complex is involved in both ubiquitin-dependent and -independent protein degradation and may contribute to the processing of antigens presented ...
Boes, Bettina +5 more
core
Striving to shed light on programming of iterative polyketide synthases (PKSs), we introduced a helix motif found in iterative PKS ketoreductase domains into an evolutionary related fatty acid synthase. With this, we were able to impose programming, switching between a reducing and nonreducing elongation mode.
Damian L. Ludig +2 more
wiley +1 more source

