PLoS ONE, 2014 Multienzyme complexes catalyze important metabolic reactions in many organisms, but little is known about the complexes involved in biological methane production (methanogenesis). A crosslinking-mass spectrometry (XL-MS) strategy was employed to identify
Dillon J Lieber +6 more
doaj +2 more sources
Performance and economic viability of broiler chicken fed diets with multienzyme complexes [PDF]
Acta Scientiarum: Animal Sciences, 2017 This study evaluated the effect of multienzyme complexes (EC1 and EC2) in low nutritional density diets on performance and economic viability of broilers. A total of 840 day-old chicks were assigned to 7 treatments, distributed in a completely randomized
Guilherme Aguiar Mateus Pasquali +5 more
doaj +4 more sources
Processive Enzymes Kept on a Leash: How Cellulase Activity in Multienzyme Complexes Directs Nanoscale Deconstruction of Cellulose. [PDF]
ACS Catal, 2021 Biological deconstruction of polymer materials gains efficiency from the spatiotemporally coordinated action of enzymes with synergetic function in polymer chain depolymerization.
Zajki-Zechmeister K +4 more
europepmc +8 more sources
Metabolic Fuel for Epigenetic: Nuclear Production Meets Local Consumption
Frontiers in Genetics, 2021 Epigenetic modifications are responsible for finetuning gene expression profiles to the needs of cells, tissues, and organisms. To rapidly respond to environmental changes, the activity of chromatin modifiers critically depends on the concentration of a ...
Ruben Boon, Ruben Boon, Ruben Boon
doaj +1 more source
Structure of the murine lysosomal multienzyme complex core [PDF]
Science Advances, 2021 The 3D structure of the complex formed by the enzymes GLB1 and CTSA furthers our understanding of lysosomal storage diseases.
Alexei Gorelik +4 more
openaire +2 more sources
Exogenous dietary enzyme formulations improve growth performance of broiler chickens fed a low-energy diet targeting the intestinal nutrient transporter genes. [PDF]
PLoS ONE, 2018 Diminishing the cost of broiler chicken diet is a critical issue in the poultry industry. Numerous studies were performed to achieve this pivotal objective by diet supplementation with alternative feed additives.
Ahmed A Saleh +5 more
doaj +1 more source
Non-translational Connections of eEF1B in the Cytoplasm and Nucleus of Cancer Cells
Frontiers in Molecular Biosciences, 2020 The human translation machinery includes three types of supramolecular complexes involved in elongation of the polypeptide chain: the ribosome, complex of elongation factors eEF1B and multienzyme aminoacyl-tRNA synthetase complex.
Boris Negrutskii
doaj +1 more source
Research progress of multi-enzyme complexes based on the design of scaffold protein
Bioresources and Bioprocessing, 2023 Multi-enzyme complexes designed based on scaffold proteins are a current topic in molecular enzyme engineering. They have been gradually applied to increase the production of enzyme cascades, thereby achieving effective biosynthetic pathways.
Xiangyi Wang +5 more
doaj +1 more source
Variation in the organization and subunit composition of the mammalian pyruvate dehydrogenase complex E2/E3BP core assembly [PDF]
, 2011 Crucial to glucose homoeostasis in humans, the hPDC (human pyruvate dehydrogenase complex) is a massive molecular machine comprising multiple copies of three distinct enzymes (E1–E3) and an accessory subunit, E3BP (E3-binding protein). Its icosahedral E2/
Swetha Vijayakrishnan +42 more
core +1 more source
Atomic structure of the cubic core of the pyruvate dehydrogenase multienzyme complex
, 1992 The highly symmetric pyruvate dehydrogenase multienzyme complexes have molecular masses ranging from 5 to 10 million daltons. They consist of numerous copies of three different enzymes: pyruvate dehydrogenase, dihydrolipoyl transacetylase, and lipoamide ...
Schulze E +6 more
core +3 more sources