Metabolic Fuel for Epigenetic: Nuclear Production Meets Local Consumption
Frontiers in Genetics, 2021 Epigenetic modifications are responsible for finetuning gene expression profiles to the needs of cells, tissues, and organisms. To rapidly respond to environmental changes, the activity of chromatin modifiers critically depends on the concentration of a ...
Ruben Boon, Ruben Boon, Ruben Boon
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Exogenous dietary enzyme formulations improve growth performance of broiler chickens fed a low-energy diet targeting the intestinal nutrient transporter genes. [PDF]
PLoS ONE, 2018 Diminishing the cost of broiler chicken diet is a critical issue in the poultry industry. Numerous studies were performed to achieve this pivotal objective by diet supplementation with alternative feed additives.
Ahmed A Saleh +5 more
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Non-translational Connections of eEF1B in the Cytoplasm and Nucleus of Cancer Cells
Frontiers in Molecular Biosciences, 2020 The human translation machinery includes three types of supramolecular complexes involved in elongation of the polypeptide chain: the ribosome, complex of elongation factors eEF1B and multienzyme aminoacyl-tRNA synthetase complex.
Boris Negrutskii
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Variation in the organization and subunit composition of the mammalian pyruvate dehydrogenase complex E2/E3BP core assembly [PDF]
, 2011 Crucial to glucose homoeostasis in humans, the hPDC (human pyruvate dehydrogenase complex) is a massive molecular machine comprising multiple copies of three distinct enzymes (E1–E3) and an accessory subunit, E3BP (E3-binding protein). Its icosahedral E2/
Swetha Vijayakrishnan +42 more
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Performance and economic viability of broiler chicken fed diets with multienzyme complexes
Acta Scientiarum: Animal Sciences, 2017 This study evaluated the effect of multienzyme complexes (EC1 and EC2) in low nutritional density diets on performance and economic viability of broilers. A total of 840 day-old chicks were assigned to 7 treatments, distributed in a completely randomized
Guilherme Aguiar Mateus Pasquali +5 more
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Research progress of multi-enzyme complexes based on the design of scaffold protein
Bioresources and Bioprocessing, 2023 Multi-enzyme complexes designed based on scaffold proteins are a current topic in molecular enzyme engineering. They have been gradually applied to increase the production of enzyme cascades, thereby achieving effective biosynthetic pathways.
Xiangyi Wang +5 more
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Information Transfer in Multienzyme Complexes [PDF]
European Journal of Biochemistry, 1997 Oxidized phosphoribulokinase is almost inactive in its isolated state but becomes active when associated with glyceraldehyde‐3‐phosphate dehydrogenase. There is therefore an information transfer that takes place between these two enzymes. However, when the complex dissociates, free oxidized phosphoribulokinase is even more active than when it is ...
Sandrine Lebreton +3 more
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Localization of the α-oxoacid dehydrogenase multienzyme complexes within the mitochondrion [PDF]
, 1990 Bovine kidney mitochondria were separated into matrix and membrane fractions by treatment with digitonin and Lubrol PX. While malate dehydrogenase was found essentially in the matrix fraction, both the pyruvate and the α-oxoglutarate dehydrogenase ...
Hans Bisswanger +3 more
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, 2023 Most enzyme catalysts are unable to achieve effective oxidation resistance because of the monotonous mimicking function or production of secondary reactive oxygen species (ROS).
Ming Li +17 more
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Elucidating the contribution of mitochondrial glutathione to ferroptosis in cardiomyocytes
Redox Biology, 2021 Ferroptosis is a programmed iron-dependent cell death associated with peroxidation of lipids particularly, phospholipids. Several studies suggested a possible contribution of mitochondria to ferroptosis although the mechanisms underlying mitochondria ...
Sehwan Jang +8 more
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