Results 41 to 50 of about 8,722 (211)

Localization of the α-oxoacid dehydrogenase multienzyme complexes within the mitochondrion

, 1990
Bovine kidney mitochondria were separated into matrix and membrane fractions by treatment with digitonin and Lubrol PX. While malate dehydrogenase was found essentially in the matrix fraction, both the pyruvate and the α-oxoglutarate dehydrogenase ...
Hans Bisswanger, Bisswanger, Hans, Edith Maas, Maas, Edith   +3 more
core   +1 more source

Transcriptome Analysis of Cyclooctasulfur Oxidation and Reduction by the Neutrophilic Chemolithoautotrophic Sulfurovum indicum from Deep-Sea Hydrothermal Ecosystems

Antioxidants, 2023
Chemolithoautotrophic Campylobacterota are widespread and predominant in worldwide hydrothermal vents, and they are key players in the turnover of zero-valence sulfur.
Shasha Wang, Lijing Jiang, Liang Cui, Karine Alain, Shaobin Xie, Zongze Shao   +5 more
doaj   +1 more source

Synthetic Multienzyme Complexes, Catalytic Nanomachineries for Cascade Biosynthesis In Vivo

, 2019
Multienzyme complexes, or metabolons, are assemblies or clusters of sequential enzymes that naturally exist in metabolic pathways. These nanomachineries catalyze the conversion of metabolites more effectively than the freely floating enzymes by ...
Jiang Xia (724344), Jiale Qu (6499385), Shannon Wing-Ngor Au (166724), Sheng Cao (215934), Rui Wang (52434), Wei Kang (175399), Tiangang Liu (1839619), Huawei Zhang (424729), Qixin Wei (7108049), Tian Ma (430725), Liang Zhang (41392), Fei Sun (102854)   +11 more
core   +1 more source

Designer cellulosomes – catalytic nanomachines with significant potential in biotechnology and circular economy

Acta Biologica Slovenica
Cellulosomes are multienzyme complexes originally found on the surface of certain anaerobic celluloytic bacteria and fungi that are specialized in the degradation of plant cell walls.
Maša Vodovnik
doaj   +1 more source

Cascade biocatalysis by multienzyme-nanoparticle assemblies

, 2014
Multienzyme complexes are of paramount importance in biosynthesis in cells. Yet, how sequential enzymes of cascade catalytic reactions synergize their activities through spatial organization remains elusive.
Nie, Yunyu, Kang, Wei, Liu, Jiahui, Xia, Jiang, Wang, Jianpeng, Guo, Zhihong   +5 more
core   +1 more source

The Molecular Origins of Specificity in the Assembly of a Multienzyme Complex [PDF]

Structure, 2005
The pyruvate dehydrogenase (PDH) multienzyme complex is central to oxidative metabolism. We present the first crystal structure of a complex between pyruvate decarboxylase (E1) and the peripheral subunit binding domain (PSBD) of the dihydrolipoyl acetyltransferase (E2).
Frank, René A.W., Pratap, J. Venkatesh, Pei, Xue Y., Perham, Richard N., Luisi, Ben F.   +4 more
openaire   +2 more sources

Oxygen Vacancy‐Enriched Platinum Single‐Atom Nanozyme Wrapped in Nanoislands: Unlocking Catalytic Activity and Reprogramming Redox Microenvironment for Osteonecrosis Repair

Advanced Science, EarlyView.
CeO2‐x/Pt single‐atom nano‐island is constructed via low‐temperature reduction, featuring abundant oxygen vacancies and an island–sea structure. It delivers outstanding multi‐enzyme‐mimetic activity and ROS‐scavenging efficiency. Density functional theory reveals optimized electronic structures and reaction pathways.
Yang Zhu, Zehui Lv, Xuejie Cai, Penghui Wei, Dengliang Wang, Zhao Wang, Ruoying Wang, Yingjie Wang, Xingdong Yang, Yixin Bian, Jiawei Xu, Xisheng Weng, Liangfeng Wei   +12 more
wiley   +1 more source

Cascade Biocatalysis by Multienzyme–Nanoparticle Assemblies

, 2016
Multienzyme complexes are of paramount importance in biosynthesis in cells. Yet, how sequential enzymes of cascade catalytic reactions synergize their activities through spatial organization remains elusive.
Jiang Xia (724344), Yunyu Nie (1368768), Jianpeng Wang (724341), Zhihong Guo (404198), Wei Kang (175399), Jiahui Liu (724342)   +5 more
core   +1 more source

Lipoate-binding proteins and specific lipoate-protein ligases in microbial sulfur oxidation reveal an atpyical role for an old cofactor

eLife, 2018
Many Bacteria and Archaea employ the heterodisulfide reductase (Hdr)-like sulfur oxidation pathway. The relevant genes are inevitably associated with genes encoding lipoate-binding proteins (LbpA).
Xinyun Cao, Tobias Koch, Lydia Steffens, Julia Finkensieper, Renate Zigann, John E Cronan, Christiane Dahl   +6 more
doaj   +1 more source

Comparative genomic analysis reveals 2-oxoacid dehydrogenase complex lipoylation correlation with aerobiosis in archaea. [PDF]

PLoS ONE, 2014
Metagenomic analyses have advanced our understanding of ecological microbial diversity, but to what extent can metagenomic data be used to predict the metabolic capacity of difficult-to-study organisms and their abiotic environmental interactions?
Kirill Borziak, Mareike G Posner, Abhishek Upadhyay, Michael J Danson, Stefan Bagby, Steve Dorus   +5 more
doaj   +1 more source