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A Multienzyme Complex for De Novo Purine Biosynthesis
1977Multienzyme complexes are defined as aggregates of different functionally related enzymes integrated into highly organized structures by non-covalent bonds. Such a structural arrangement is considered to confer a catalytic advantage in that an unstable intermediate may be transferred more efficiently from one active site to the next.
P B, Rowe +3 more
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Multienzyme assembly of a p53 transcription complex
Nature Structural & Molecular Biology, 2007Proline isomerization of the p53 transactivation domain has a central role in coordinating kinase signaling pathways that assemble the core p53 transcription complex.
Ted R Hupp, Malcolm Walkinshaw
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Regulation of the Mitochondrial Multienzyme Complexes in Complex Metabolic Systemsa
Annals of the New York Academy of Sciences, 1989During the past two decades, I and the members of my laboratory have enjoyed very much contributing to the body of knowledge concerning the alpha-keto acid dehydrogenase complexes. We would hope that some of our work has allowed those interested in this area a perception as to how these interesting enzyme complexes are regulated in intact metabolic ...
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[Structure-activity relationships in multienzyme complexes].
Molekuliarnaia biologiia, 1996Structures and molecular kinetic models of function of 2-oxo acid dehydrogenase complexes were analyzed. It was suggested that identical protein subunits in the multienzyme complexes as in the structure capable of self-assembly have identical contacts with the neighbors and identical environment.
B N, Gol'dshteĭn +2 more
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Synthetic Multienzyme Complexes, Catalytic Nanomachineries for Cascade Biosynthesis In Vivo
ACS Nano, 2019Tiangang Liu, Jiang Xia, Fei Sun
exaly
Purification of multienzyme complexes.
Methods in enzymology, 1990P A, Srere, C K, Mathews
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