Results 241 to 250 of about 6,631,648 (289)

The pyruvate dehydrogenase multienzyme complex

Current Opinion in Structural Biology, 1992
Abstract During the review period, several structures of component enzymes and domains of enzymes of this multienzyme complex were determined. Three structures of the flavoprotein component, dihydrolipoamide dehydrogenase, became available. The structure of the core component, dihydrolipoyl acetyltransferase, can in principle be constructed from the ...
Andrea Mattevi, Aart de Kok, Richard N. Perham   +2 more
openaire   +1 more source

Regulation of the Pyruvate Dehydrogenase Multienzyme Complex

Annual Review of Nutrition, 1993
To maximize catalytic efficiency in metabolic pathways of both prokaryotic and eUkaryotic cells, enzymatic components are occasionally clustered or complexed physically. Organization of multiple catalytic functions into a single enzyme complex can be accomplished in two ways.
R H, Behal, D B, Buxton, J G, Robertson, M S, Olson   +3 more
openaire   +3 more sources

Phase Separation-Mediated Multienzyme Assembly In Vivo.

Journal of Agricultural and Food Chemistry
Multienzyme assembly catalysis is a cornerstone of synthetic biology. In this study, we integrated the phase-separated protein RGGRGG with the ReverseTag/ReverseCatcher tagging system to investigate its potential for multienzyme complex formation ...
Yao Chen, Yi Shi, Mengyu Li, Dengming Ming, Wei Liu, Xian Xu, Ling Jiang   +6 more
semanticscholar   +1 more source

The Pyruvate Dehydrogenase Multienzyme Complex

Angewandte Chemie International Edition in English, 1975
AbstractThe three enzymes pyruvate dehydrogenase, dihydrolipoamide transacetylase, and dihydrolipoamide dehydrogenase constitute the pyruvate dehydrogenase multienzyme complex of E. coli; in mammals the complex also contains a kinase and a phosphatase.
openaire   +2 more sources

Multienzyme Complex in Fatty Acid Biosynthesis

2023
Fatty acid biosynthesis is a fundamental process that occurs in all living organisms and involves multiple reaction steps. Thus, a systematic transfer of the intermediates between the different catalytic sites is highly required for the efficient regulation of a pathway as well as for sustaining growth.
Pranesha Prabhakaran, Yusuf Nazir, Hafiy Halim, Aidil Abdul Hamid, Yuanda Song   +4 more
openaire   +1 more source

A Multienzyme Bioreactor Based on a Chitinase Complex

Прикладная биохимия и микробиология, 2014
A heterogeneous biocatalyst containing a complex of chitinolytic enzymes isolated from the culture medium of bacteria Clostridium paraputrificum on the surface of macroporous monolithic minidisc was obtained. The complex of chitinolytic enzymes was immobilized on the polymer matrix using a multistep method involving the introduction of an intermediate ...
E G, Vlakh, E A, Ponomareva, T B, Tennikova   +2 more
openaire   +2 more sources

Research progress and the biotechnological applications of multienzyme complex

Applied Microbiology and Biotechnology, 2021
The multienzyme complex system has become a research focus in synthetic biology due to its highly efficient overall catalytic ability and has been applied to various fields. Multienzyme complexes are formed by cascading complexes, which are multiple functionally related enzymes that continuously and efficiently catalyze the production of substrates ...
Yi Jiang, Xinyi Zhang, Haibo Yuan, Di Huang, Ruiming Wang, Hongling Liu, Tengfei Wang   +6 more
openaire   +2 more sources

[Symmetry of multienzyme complexes].

Molekuliarnaia biologiia, 1986
A model for studying the symmetry of stable states arising from polyenzymic complex conformations is proposed. A formal scheme of submolecular structure self-assembly, on which the model is based, enables it not only to limit the class of conformations but in some cases to determine the structure of a complex in an unambigous manner. The model is shown
B N, Gol'dshteĭn, V V, Kornilov, Ia S, Smetanich   +2 more
openaire   +1 more source

4 Multienzyme Complexes

1970
Publisher Summary This chapter discusses certain features of a few well-documented examples of multienzyme complexes. The multienzyme complexes that have been most thoroughly described are composed of two to six functionally related enzymes and have molecular weights ranging from a few hundred thousand to a few million. The particles contain definite
openaire   +1 more source

Multienzyme assembly of a p53 transcription complex

Nature Structural & Molecular Biology, 2007
Proline isomerization of the p53 transactivation domain has a central role in coordinating kinase signaling pathways that assemble the core p53 transcription complex.
Ted R Hupp, Malcolm Walkinshaw
openaire   +1 more source