Processive Enzymes Kept on a Leash: How Cellulase Activity in Multienzyme Complexes Directs Nanoscale Deconstruction of Cellulose. [PDF]
ACS Catal, 2021 Biological deconstruction of polymer materials gains efficiency from the spatiotemporally coordinated action of enzymes with synergetic function in polymer chain depolymerization.
Zajki-Zechmeister K +4 more
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The analysis of metabolite channelling in multienzyme complexes and multifunctional proteins [PDF]
Biochemical Journal, 1989 Multienzyme complexes and multifunctional proteins may confer a kinetic advantage by channelling reaction intermediates between consecutive enzymes and reducing the transient time for the establishment of steady states. A general means for quantitatively assessing the contribution of channelling to the reduction of pool size and transient time is ...
J. S. Easterby
openaire +4 more sources
Cell-surface Attachment of Bacterial Multienzyme Complexes Involves Highly Dynamic Protein-Protein Anchors. [PDF]
J Biol Chem, 2015 Background: Cohesin-dockerin interactions support the binding of multienzyme complexes (cellulosomes) onto the cell surface. Results: The structures of novel Coh-Doc complexes reveal a dual binding mode.
Cameron K +9 more
europepmc +2 more sources
Active site coupling in multienzyme complexes [PDF]
Acta Crystallographica Section A Foundations of Crystallography, 2005 Rainer Frank +4 more
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Production of Biomass-Degrading Multienzyme Complexes under Solid-State Fermentation of Soybean Meal Using a Bioreactor. [PDF]
Enzyme Res, 2012 Biomass-degrading enzymes are one of the most costly inputs affecting the economic viability of the biochemical route for biomass conversion into biofuels.
Vitcosque GL +5 more
europepmc +2 more sources
Multienzyme complexes and hydrogen transfer: the work of Perry Frey. [PDF]
J Biol Chem, 2009 Quaternary Structure of Pyruvate Dehydrogenase Complex from Esherichia coli (Yang, H. C., Hainfeld, J. F., Wall, J. S., and Frey, P. A. (1985) J. Biol. Chem. 260, 16049–16051) Lysine 2,3-Aminomutase. Support for a Mechanism of Hydrogen Transfer Involving S-Adenosylmethionine (Baraniak, J., Moss, M. L., and Frey, P. A. (1989) J. Biol. Chem. 264, 1357–
Kresge N, Simoni RD, Hill RL.
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Richard Nelson Perham. 27 April 1937—14 February 2015 [PDF]
, 2018 Richard Nelson Perham, FRS, FMedSci, FRSA, was a British professor of structural biochemistry. He undertook his academic career at the University of Cambridge, holding positions as lecturer, reader, chair and head of the Department of Biochemistry, as ...
Charoy, François +6 more
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Synthetic Multienzyme Assemblies for Natural Product Biosynthesis
ChemBioChem, 2023 In nature, enzymes that catalyze sequential reactions are often assembled as clusters or complexes. The formation of multienzyme complexes, or metabolons, brings the enzyme active sites into proximity to promote intermediate transfer, decrease ...
Min Liu +4 more
semanticscholar +1 more source
Bioconjugate chemistry, 2020 Multienzyme complexes, or metabolons, are natural assemblies or clusters of sequential enzymes in biosynthesis. Spatial proximity of the enzyme active sites results in a substrate channeling effect, streamlines the cascade reaction, and increases the ...
Qixin Wei, Sicong He, J. Qu, Jiang Xia
semanticscholar +1 more source
Self-Organization and Information Processing: from Basic Enzymatic Activities to Complex Adaptive Cellular Behavior [PDF]
, 2021 One of the main aims of current biology is to understand the origin of the molecular organization that underlies the complex dynamic architecture of cellular life.
Carrasco Pujante, José +5 more
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