Results 41 to 50 of about 6,631,648 (289)

Abstract OR-3: Fleeting Ensembles: Transient Protein-Protein Interactions in DNA Repair [PDF]

International Journal of Biomedicine, 2019
Background: DNA repair is a vitally important process that protects the cell’s genome from ongoing damage. Six DNA repair pathways are commonly outlined: direct reversal, base excision repair, nucleotide excision repair, mismatch repair, recombination ...
Dmitry O. Zharkov
doaj   +1 more source

Secretion and assembly of functional mini-cellulosomes from synthetic chromosomal operons in Clostridium acetobutylicum ATCC 824. [PDF]

, 2013
Background: Consolidated bioprocessing (CBP) is reliant on the simultaneous enzyme production, saccharification of biomass, and fermentation of released sugars into valuable products such as butanol. Clostridial species that produce butanol are, however,
Bolam, DN, Heap, JT, Jackson, A, Kovács, K, Minton, NP, Schwarz, K, Willson, BJ, Winzer, K   +7 more
core   +1 more source

Performance and economic viability of broiler chicken fed diets with multienzyme complexes

, 2017
This study evaluated the effect of multienzyme complexes (EC1 and EC2) in low nutritional density diets on performance and economic viability of broilers. A total of 840 day-old chicks were assigned to 7 treatments, distributed in a completely randomized
Guilherme A M Pasquali, Raphael Fortes de Oliveira, Paula Andressa Bedim Aiello, G. V. Polycarpo, R. Crivellari, V. C. Cruz-Polycarpo   +5 more
semanticscholar   +1 more source

Characterization of the mycobacterial acyl-CoA carboxylase holo complexes reveals their functional expansion into amino acid catabolism.

PLoS Pathogens, 2015
Biotin-mediated carboxylation of short-chain fatty acid coenzyme A esters is a key step in lipid biosynthesis that is carried out by multienzyme complexes to extend fatty acids by one methylene group.
Matthias T Ehebauer, Michael Zimmermann, Arjen J Jakobi, Elke E Noens, Daniel Laubitz, Bogdan Cichocki, Hedia Marrakchi, Marie-Antoinette Lanéelle, Mamadou Daffé, Carsten Sachse, Andrzej Dziembowski, Uwe Sauer, Matthias Wilmanns   +12 more
doaj   +1 more source

Mitochondrial Enzymes of the Urea Cycle Cluster at the Inner Mitochondrial Membrane

Frontiers in Physiology, 2021
Mitochondrial enzymes involved in energy transformation are organized into multiprotein complexes that channel the reaction intermediates for efficient ATP production.
Nantaporn Haskins, Shivaprasad Bhuvanendran, Claudio Anselmi, Claudio Anselmi, Anna Gams, Tomas Kanholm, Kristen M. Kocher, Jonathan LoTempio, Kylie I. Krohmaly, Danielle Sohai, Nathaniel Stearrett, Nathaniel Stearrett, Erin Bonner, Mendel Tuchman, Hiroki Morizono, Hiroki Morizono, Jyoti K. Jaiswal, Jyoti K. Jaiswal, Ljubica Caldovic, Ljubica Caldovic   +19 more
doaj   +1 more source

Structure–function analyses generate novel specificities to assemble the components of multienzyme bacterial cellulosome complexes

Journal of Biological Chemistry, 2018
The cellulosome is a remarkably intricate multienzyme nanomachine produced by anaerobic bacteria to degrade plant cell wall polysaccharides. Cellulosome assembly is mediated through binding of enzyme-borne dockerin modules to cohesin modules of the ...
P. Bule, K. Cameron, J. Prates, L. Ferreira, Steven P. Smith, H. Gilbert, E. Bayer, S. Najmudin, C. Fontes, V. Alves   +9 more
semanticscholar   +1 more source

Block copolymer-quantum dot micelles for multienzyme colocalization [PDF]

, 2012
To mimic the structure and functionality of multienzyme complexes, which are widely present in Nature, Pluronic-based micelles were designed to colocalize multiple enzymes.
Jia, Feng, Mallapragada, Surya, Mallapragada, Surya, Narasimhan, Balaji, Narasimhan, Balaji, Zhang, Yanjie   +5 more
core   +3 more sources

Engineering of Metabolic Pathways by Artificial Enzyme Channels. [PDF]

, 2015
Application of industrial enzymes for production of valuable chemical compounds has greatly benefited from recent developments in Systems and Synthetic Biology.
Boccaccini, AR, Detsch, R, Pröschel, M, Sonnewald, U   +3 more
core   +3 more sources

Properties of Lactic Acid Microorganisms: Long-Term Preservation Methods [PDF]

Техника и технология пищевых производств, 2018
Among the relevant studies on lactic acid bacteria there are projects devoted to the multienzyme complexes of starter cultures, new competitive bacterial concentrates and their use in fermented functional milk products.
Kriger O., Noskova S.
doaj   +1 more source

Cellular localization of the hybrid pyruvate/2-oxoglutarate dehydrogenase complex in the actinobacterium Corynebacterium glutamicum

Microbiology Spectrum, 2023
For many bacterial proteins, specific localizations within the cell have been demonstrated, but enzymes involved in central metabolism are usually considered to be homogenously distributed within the cytoplasm. Here, we provide an example for a spatially
Lea Sundermeyer, Jan-Gerrit Folkerts, Benita Lückel, Christina Mack, Meike Baumgart, Michael Bott   +5 more
doaj   +1 more source