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Seminars in Neurology, 1998
Abstract Multifocal motor neuropathy (MMN) is an acquired, immune-mediated, chronic demyelinating neuropathy. Clinically, it is characterized by slowly progressive asymmetrical weakness without sensory involvement. Electrophysiological testing reveals multifocal motor demyelinating features with partial motor conduction block.
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Abstract Multifocal motor neuropathy (MMN) is an acquired, immune-mediated, chronic demyelinating neuropathy. Clinically, it is characterized by slowly progressive asymmetrical weakness without sensory involvement. Electrophysiological testing reveals multifocal motor demyelinating features with partial motor conduction block.
exaly +7 more sources
Treatment of multifocal motor neuropathy
Neurological Sciences, 2003 Multifocal motor neuropathy (MMN) is a purely motor multineuropathy characterized by multifocal conduction blocks on motor nerves. The pathogenesis of MMN is not known but its frequent association with anti-ganglioside antibodies and the improvement after immune therapies support an immune pathogenesis.
E. Nobile-Orazio +3 more
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Seminars in Neurology, 2013
Multifocal motor neuropathy (MMN) is a rare disorder in which the symptoms are caused by persistent conduction block lesions. The mononeuropathy multiplex progresses over time with increasing axonal loss. The cause of the conduction blocks and axonal loss are not completely understood but immune mechanisms are involved and response to intravenous ...
Ximena, Arcila-Londono, Richard A, Lewis
+9 more sources
Multifocal motor neuropathy (MMN) is a rare disorder in which the symptoms are caused by persistent conduction block lesions. The mononeuropathy multiplex progresses over time with increasing axonal loss. The cause of the conduction blocks and axonal loss are not completely understood but immune mechanisms are involved and response to intravenous ...
Ximena, Arcila-Londono, Richard A, Lewis
+9 more sources
Multifocal motor neuropathy: Current concepts and controversiesâ€
Muscle and Nerve, 2005 Multifocal motor neuropathy (MMN) is now a well-defined purely motor multineuropathy characterized by the presence of multifocal partial motor conduction blocks (CB), frequent association with anti-GM1 IgM antibodies, and usually a good response to high ...
Alberto Priori, Eduardo Nobile-Orazio
exaly +2 more sources
Neurologic Clinics, 1992
We believe that our present understanding of these syndromes is insufficient to separate CIDP from MMN clearly and consider MMN to be a remarkably multifocal, predominantly motor variant of CIDP with the very unusual electrophysiologic feature of conduction block confined to motor axons.
G J, Parry, A J, Sumner
+5 more sources
We believe that our present understanding of these syndromes is insufficient to separate CIDP from MMN clearly and consider MMN to be a remarkably multifocal, predominantly motor variant of CIDP with the very unusual electrophysiologic feature of conduction block confined to motor axons.
G J, Parry, A J, Sumner
+5 more sources
Acute motor neuropathy with pure distal involvement – A case report of multifocal motor neuropathy
European Journal of Paediatric Neurology, 2013 Multifocal Motor Neuropathy is an acquired pure motor neuropathy seen principally in adults and usually responds to treatment with intravenous immunoglobulin.
Sithara Ramdas +2 more
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Journal of Neurology, 1997
We present a review of the literature on multifocal motor neuropathy (MMN), a rare neurological disorder which has features in common with both chronic inflammatory demyelinating neuropathy and lower motor neuron disease. Clinically, MMN is characterised by slowly progressive asymmetrical limb weakness, usually most prominent in the forearms.
Biessels, G.J. +6 more
openaire +4 more sources
We present a review of the literature on multifocal motor neuropathy (MMN), a rare neurological disorder which has features in common with both chronic inflammatory demyelinating neuropathy and lower motor neuron disease. Clinically, MMN is characterised by slowly progressive asymmetrical limb weakness, usually most prominent in the forearms.
Biessels, G.J. +6 more
openaire +4 more sources
Neurology India, 2011
Multifocal motor neuropathy (MMN) is a unique disorder characterized by slowly progressive, asymmetric, distal and upper limb predominant weakness without significant sensory abnormalities. Electrophysiology is crucial to the diagnosis, revealing the hallmark partial conduction block.
Thy P, Nguyen, Vinay, Chaudhry
openaire +2 more sources
Multifocal motor neuropathy (MMN) is a unique disorder characterized by slowly progressive, asymmetric, distal and upper limb predominant weakness without significant sensory abnormalities. Electrophysiology is crucial to the diagnosis, revealing the hallmark partial conduction block.
Thy P, Nguyen, Vinay, Chaudhry
openaire +2 more sources
Neurology, 2006
Recognition of new clinical phenotypes requires knowledge and clinical experience together with a new insight, often provided by an unexpected test result. Sometimes, as in multifocal motor neuropathy (MMN), the abnormal test result becomes the gold standard for diagnosis, superceding the clinical phenotype that initially defined the syndrome.
Vinay Chaudhry, Michael Swash
+5 more sources
Recognition of new clinical phenotypes requires knowledge and clinical experience together with a new insight, often provided by an unexpected test result. Sometimes, as in multifocal motor neuropathy (MMN), the abnormal test result becomes the gold standard for diagnosis, superceding the clinical phenotype that initially defined the syndrome.
Vinay Chaudhry, Michael Swash
+5 more sources
Treatment of Multifocal Motor Neuropathy
Current Treatment Options in Neurology, 2014Multifocal motor neuropathy (MMN) is a treatable immune disorder of the peripheral nerves that is characterized clinically by slowly progressive or stepwise asymmetric distal > proximal, upper > lower limb weakness in multiple motor nerve distributions; electrophysiologically by multifocal motor demyelination, specifically partial motor conduction ...
Madhavi, Jinka, Vinay, Chaudhry
openaire +2 more sources