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A misdiagnosis of multifocal motor neuropathy
The Lancet Neurology, 2003A 60-year-old man had progressive asymmetric weakness in his arms and legs for 11 years. The weakness first appeared in the distal muscles and progressed to involve the proximal muscles in the left leg. 5 years into the illness the patient developed distal weakness in his left hand, which spread to involve his left forearm, arm, and shoulder girdle ...
Jeyaraj D, Pandian, Pooja, Khosla
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Immunoadsorption in Multifocal Motor Neuropathy
Journla of Immunotherapy, 1999To our knowledge, this is the first reported application of immunoadsorption in a patient with multifocal motor neuropathy (MMN). The diagnosis relied on the typical clinical features, markedly increased IgM-GM1 antibodies, multiple motor conduction blocks, and motor nerve biopsy.
J, Finsterer, K, Derfler
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Immunotherapy of multifocal motor neuropathy
Expert Opinion on Biological Therapy, 2011Multifocal motor neuropathy (MMN) is an immune-mediated disease, which usually runs a chronic course. Current treatments are aiming at modulation of the immune response to maintain functional status. Although patients can remain stable with prolonged maintenance intravenous immunoglobuin (IVIg) treatment, most patients slowly deteriorate over many ...
Filip, Eftimov, Ivo N, Van Schaik
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Brain and nerve = Shinkei kenkyu no shinpo
Multifocal motor neuropathy (MMN) is a very rare inflammatory neuropathy that leads to muscle weakness in mainly the hands and feet. IgM antibodies directed against the ganglioside GM1 can be found in at least 50% of patients with MMN, which upon binding to neurons activate the classical pathway of the complement cascade, leading to motor neuron damage.
So, Kanda, Takashi, Kanda
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Multifocal motor neuropathy (MMN) is a very rare inflammatory neuropathy that leads to muscle weakness in mainly the hands and feet. IgM antibodies directed against the ganglioside GM1 can be found in at least 50% of patients with MMN, which upon binding to neurons activate the classical pathway of the complement cascade, leading to motor neuron damage.
So, Kanda, Takashi, Kanda
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2014
Multifocal motor neuropathy (MMN) is a well-defined purely motor mononeuropathy multiplex characterized by the presence of partial conduction blocks in motor nerves, frequent association with anti-GM1 IgM antibodies, and usually a good response to high-dose intravenous immunoglobulin (IVIg) therapy.
E. Nobile-Orazio, F. Gallia
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Multifocal motor neuropathy (MMN) is a well-defined purely motor mononeuropathy multiplex characterized by the presence of partial conduction blocks in motor nerves, frequent association with anti-GM1 IgM antibodies, and usually a good response to high-dose intravenous immunoglobulin (IVIg) therapy.
E. Nobile-Orazio, F. Gallia
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[Multifocal motor neuropathy].
Revista de neurologia, 2000The multifocal motor neuropathy is an immunological disease that courses with an asymmetrical distal weakness, usually predominant in the upper limbs.It is not rarely misdiagnosed as a motoneurone disease because of the frequent occurrence of fasciculations and cramps and the absence of sensory symptoms. Neurophysiological studies are essential for the
A, Traba, A, Esteban
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The Journal of the Association of Physicians of India, 2003
A brief report of four patients with Multifocal Motor Neuropathy (MMN) two of whom improved with cyclophosphamide is presented. This is the first report of MMN from India.
K R, Nair, J, Jose
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A brief report of four patients with Multifocal Motor Neuropathy (MMN) two of whom improved with cyclophosphamide is presented. This is the first report of MMN from India.
K R, Nair, J, Jose
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Consensus criteria for the diagnosis of multifocal motor neuropathy†‡§
Muscle and Nerve, 2003Richard Knox Olney, Joseph V Campellone
exaly