Extreme multifunctional proteins identified from a human protein interaction network. [PDF]
Nat Commun, 2015 International audienceMoonlighting proteins are a subclass of multifunctional proteins whose functions are unrelated. Although they may play important roles in cells, there has been no large-scale method to identify them, nor any effort to characterize ...
Chapple CE +5 more
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Multiple Forms of Multifunctional Proteins in Health and Disease [PDF]
Frontiers in Cell and Developmental Biology, 2020 Protein science has moved from a focus on individual molecules to an integrated perspective in which proteins emerge as dynamic players with multiple functions, rather than monofunctional specialists.
Adriana Espinosa-Cantú +3 more
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Making Sense of Multifunctional Proteins: Human Immunodeficiency Virus Type 1 Accessory and Regulatory Proteins and Connections to Transcription. [PDF]
Annu Rev Virol, 2017 Viruses are completely dependent upon cellular machinery to support replication and have therefore developed strategies to co-opt cellular processes to optimize infection and counter host immune defenses.
Faust TB +3 more
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RNA-Binding Proteins in Trichomonas vaginalis: Atypical Multifunctional Proteins [PDF]
Biomolecules, 2015 Iron homeostasis is highly regulated in vertebrates through a regulatory system mediated by RNA-protein interactions between the iron regulatory proteins (IRPs) that interact with an iron responsive element (IRE) located in certain mRNAs, dubbed the IRE-
Elisa E. Figueroa-Angulo +3 more
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Multifunctional oral delivery systems for enhanced bioavailability of therapeutic peptides/proteins
Acta Pharmaceutica Sinica B, 2019 In last few years, therapeutic peptides/proteins are rapidly growing in drug market considering their higher efficiency and lower toxicity than chemical drugs.
Ying Han +7 more
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Structural variability of multifunctional proteins indicates frequent stochastic evolution of protein oligomers [PDF]
Communications BiologyRecently, it has been suggested that the evolution of many protein homomer complexes follows a neutral pattern, with little effect on their biochemical function.
György Abrusán, Aleksej Zelezniak
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Catcher Domains as Multifunctional Fusion Modules for Soluble Expression, Covalent Coupling, and Spatial Organization of Recombinant Proteins [PDF]
Small ScienceFusion tags are essential tools for recombinant protein production, but their functions are often limited to improving solubility or facilitating purification.
Ruxia Fan +6 more
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An alternative vaccine target for bovine Anaplasmosis based on enolase, a moonlighting protein
Frontiers in Veterinary Science, 2023 The discovery of new targets for preventing bovine anaplasmosis has moved away from focusing on proteins that have already been extensively studied in Anaplasma marginale, including the Major Surface Proteins, Outer Membrane Proteins, and Type IV ...
Rosa Estela Quiroz-Castañeda +2 more
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Pharmaceutics, 2023 A large number of proteins are successfully used to treat various diseases. These include natural polypeptide hormones, their synthetic analogues, antibodies, antibody mimetics, enzymes, and other drugs based on them.
Andrey A. Rosenkranz +1 more
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20S and 26S proteasome-binding proteins of the rabbit brain: A proteomic dataset
Data in Brief, 2021 Fractions of 26S and 20S proteasomes isolated from the rabbit brain by the method of salt fractionation (salt-induced precipitation) contain intrinsic proteasome proteins responsible for assembly of the core particle and regulatory particle of proteasome
Olga Buneeva +4 more
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