Results 21 to 30 of about 1,913,001 (298)

Therapeutic Potential of Engineered Virus-like Particles of Parvovirus B19

Pathogens, 2023
Virus-like particles (VLPs) comprise one or many structural components of virions, except their genetic material. Thus, VLPs keep their structural properties of cellular recognition while being non-infectious.
Ignacio Sánchez-Moguel, Carmina Montiel, Ismael Bustos-Jaimes   +2 more
doaj   +1 more source

The Coronavirus Nucleocapsid Is a Multifunctional Protein [PDF]

Viruses, 2014
The coronavirus nucleocapsid (N) is a structural protein that forms complexes with genomic RNA, interacts with the viral membrane protein during virion assembly and plays a critical role in enhancing the efficiency of virus transcription and assembly. Recent studies have confirmed that N is a multifunctional protein.
Ruth McBride, Marjorie Van Zyl, Burtram Fielding   +2 more
openaire   +4 more sources

Intrinsic Disorder and Posttranslational Modifications: The Darker Side of the Biological Dark Matter

Frontiers in Genetics, 2018
Intrinsically disordered proteins (IDPs) and intrinsically disordered protein regions (IDPRs) are functional proteins and domains that devoid stable secondary and/or tertiary structure.
April L. Darling, Vladimir N. Uversky, Vladimir N. Uversky   +2 more
doaj   +1 more source

P40 and P90 from Mpn142 are Targets of Multiple Processing Events on the Surface of Mycoplasma pneumoniae

Proteomes, 2015
Mycoplasma pneumoniae is a significant cause of community acquired pneumonia globally. Despite having a genome less than 1 Mb in size, M. pneumoniae presents a structurally sophisticated attachment organelle that (i) provides cell polarity, (ii) directs ...
Michael Widjaja, Iain J. Berry, Elsa J. Pont, Matthew P. Padula, Steven P. Djordjevic   +4 more
doaj   +1 more source

The multifunctional NS1 protein of influenza A viruses [PDF]

, 2012
The non-structural (NS1) protein of influenza A viruses is a non-essential virulence factor that has multiple accessory functions during viral infection.
Hale, Benjamin Geoffrey, Randall, Richard Edward, Jackson, David, Ortin, J   +3 more
core   +2 more sources

Multiple horizontal gene transfer events and domain fusions have created novel regulatory and metabolic networks in the oomycete genome.

PLoS ONE, 2009
Complex enzymes with multiple catalytic activities are hypothesized to have evolved from more primitive precursors. Global analysis of the Phytophthora sojae genome using conservative criteria for evaluation of complex proteins identified 273 novel ...
Paul Francis Morris, Laura Rose Schlosser, Katherine Diane Onasch, Tom Wittenschlaeger, Ryan Austin, Nicholas Provart   +5 more
doaj   +1 more source

14-3-3 Proteins Interact with a Hybrid Prenyl-Phosphorylation Motif to Inhibit G Proteins [PDF]

, 2013
Signaling through G proteins normally involves conformational switching between GTP- and GDP-bound states. Several Rho GTPases are also regulated by RhoGDI binding and sequestering in the cytosol.
Riou, P, O’Reilly, N., George, Roger, Ritu Garg, McColl, Brad, Ganka Bineva, Kjær, S., Svend Kjær, Garg, R, Bineva, G., Thompson, AJ, Reymond, N, Philippe Riou, Purkiss, Andrew, Nicola O’Reilly, Parker, Peter J, Brad McColl, Peter J. Parker, Neil Q. McDonald, Parker, Peter J.; id_orcid, Riou, P., Purkiss, A, Parker, PJ, Thompson, A.J., McColl, B, Cain, RJ, Parker, P.J., Kjær, Svend, McColl, B., Andrew Purkiss, O’Reilly, N, Kjær, S, Garg, R., Garg, Ritu, O'Reilly, Nicola, Anne J. Ridley, Cain, Robert J, Robert J. Cain, McDonald, Neil Q, Ridley, Anne J, Bineva, G, Ridley, A.J., Purkiss, Andrew G., Nicolas Reymond, George, R., Thompson, Andrew J, Reymond, N., Reymond, Nicolas, Bineva, Ganka, McDonald, NQ, Riou, Philippe, Andrew J. Thompson, Ridley, AJ, Kjaer, Svend, George, R, Cain, R.J., Roger George, McDonald, Neil Q., Thompson, Andrew J., Cain, Robert J., Ridley, Anne J.   +60 more
core   +1 more source

Food-derived multifunctional bioactive proteins and peptides: Sources and production

, 2015
© 2015 by John Wiley & Sons, Ltd. All rights reserved. Multifunctional proteins and peptides from food proteins have been studied over the past few decades to elucidate their biological potency and the beneficial roles they play in human health. Owing to
Potumarthi, R., Agyei, D., Ravichandra Potumarthi, Dominic Agyei, Michael K. Danquah, Danquah, Michael   +5 more
core   +2 more sources

The multifunctional GIT family of proteins [PDF]

Journal of Cell Science, 2006
The G-protein-coupled receptor (GPCR)-kinase-interacting proteins 1 and 2 (GIT1 and GIT2) are ubiquitous multidomain proteins involved in diverse cellular processes. They traffic between three distinct cellular compartments (cytoplasmic complexes, focal adhesions and the cell periphery) through interactions with proteins including ARF, Rac1 and Cdc42 ...
Ryan J, Hoefen, Bradford C, Berk
openaire   +2 more sources

Controlled self-assembly of plant proteins into high-performance multifunctional nanostructured films

Nature Communications, 2021
Green use of plant derived proteins in functional materials has been limited by inefficient methods to control micro and nanoscale structure. Here, the authors use nanoscale assembly of water-insoluble plant proteins to make meter scale films with ...
Ayaka Kamada, Marc Rodriguez-Garcia, Francesco Simone Ruggeri, Yi Shen, Aviad Levin, Tuomas P. J. Knowles   +5 more
doaj   +1 more source