Results 11 to 20 of about 1,913,001 (298)
Multifunctional Microtubule-Associated Proteins in Plants [PDF]
Frontiers in Plant Science, 2016 Microtubules (MTs) are involved in key processes in plant cells, including cell division, growth and development. MT-interacting proteins modulate MT dynamics and organization, mediating functional and structural interaction of MTs with other cell ...
Jana eKrtková +4 more
doaj +2 more sources
Multifunctional Proteins Bridge Mitosis with Motility and Cancer with Inflammation and Arthritis [PDF]
The Scientific World Journal, 2010 While most secreted proteins contain defined signal peptides that direct their extracellular transport through the ER-Golgi pathway, nonclassical transport of leaderless peptides/proteins was first described 20 years ago and the mechanisms responsible ...
Jihong Jiang +5 more
doaj +2 more sources
BiomoleculesPrevious reports indicated that self-assembling amphipathic peptide S1v1 (AEAEAHAH)2 significantly enhances the soluble expression, thermostability, and activity of the target proteins when fused to them.
Jun Yang +8 more
doaj +2 more sources
ComputationProtein embedding is a protein representation that carries along the information derived from filtering large volumes of sequences stored in large archives.
Gabriele Vazzana +4 more
doaj +2 more sources
Multifunctional Proteins: Involvement in Human Diseases and Targets of Current Drugs. [PDF]
Protein J, 2018 Multifunctionality or multitasking is the capability of some proteins to execute two or more biochemical functions. The objective of this work is to explore the relationship between multifunctional proteins, human diseases and drug targeting.
Franco-Serrano L +8 more
europepmc +2 more sources
Moonlighting in Mitosis: Analysis of the Mitotic Functions of Transcription and Splicing Factors
Cells, 2020 Moonlighting proteins can perform one or more additional functions besides their primary role. It has been posited that a protein can acquire a moonlighting function through a gradual evolutionary process, which is favored when the primary and secondary ...
Maria Patrizia Somma +8 more
doaj +1 more source
p73: A Multifunctional Protein in Neurobiology [PDF]
Molecular Neurobiology, 2011 p73, a transcription factor of the p53 family, plays a key role in many biological processes including neuronal development. Indeed, mice deficient for both TAp73 and ΔNp73 isoforms display neuronal pathologies, including hydrocephalus and hippocampal dysgenesis, with defects in the CA1-CA3 pyramidal cell layers and the dentate gyrus.
Killick, R +15 more
openaire +5 more sources
Lasso-grafting of macrocyclic peptide pharmacophores yields multi-functional proteins
Nature Communications, 2021 RaPID (Random non-standard Peptides Integrated Discovery) enables discovery of small macrocyclic peptides binding desired targets. Here, the authors propose lasso-grafting: the RaPID-derived peptides are implanted onto diverse proteins and maintain both ...
Emiko Mihara +12 more
doaj +1 more source
Arabinogalactan proteins – Multifunctional glycoproteins of the plant cell wall
The Cell Surface, 2023 Arabinogalactan-proteins (AGPs) are cell wall glycoproteins that make up a relatively small component of the extracellular matrix of plants yet have significant influence on wall mechanics and signalling.
Yingxuan Ma, Kim Johnson
doaj +1 more source
DDX20: A Multifunctional Complex Protein
Molecules, 2023 DEAD-box decapping enzyme 20 (DDX20) is a putative RNA-decapping enzyme that can be identified by the conserved motif Asp–Glu–Ala–Asp (DEAD). Cellular processes involve numerous RNA secondary structure alterations, including translation initiation, nuclear and mitochondrial splicing, and assembly of ribosomes and spliceosomes. DDX20 reportedly plays an
Lu He +14 more
openaire +3 more sources