Electron transfer pathways in a multiheme cytochrome MtrF [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 2017 In MtrF, an outer-membrane multiheme cytochrome, the 10 heme groups are arranged in heme binding domains II and IV along the pseudo-C2 axis, forming the electron transfer (ET) pathways. Previous reports based on molecular dynamics simulations showed that
Hiroshi Ishikita +2 more
exaly +3 more sources
The modular evolution of multiheme cytochromes c bucks the general trend observed in most proteins
Protein Science, Volume 35, Issue 9, September 2026.Abstract Multiheme cytochromes c are versatile enzymes which contribute to key steps in diverse biogeochemical cycles of chemical elements such as nitrogen, iron, and sulfur, and are also key players in microbial electrochemical technologies. Understanding how they evolved offers a blueprint on how nature tuned their sequence and heme c cofactors to ...
Ricardo Soares +2 more
wiley +2 more sources
Efficient and selective isotopic labeling of hemes to facilitate the study of multiheme proteins
BioTechniques, 2012 Specific isotopic labeling of hemes provides a unique opportunity to characterize the structure and function of heme-proteins. Unfortunately, current methods do not allow efficient labeling in high yields of multiheme cytochromes c, which are of great ...
Bruno M. Fonseca +4 more
doaj +2 more sources
Advancing the Resolution of the Sulfur Compound Disproportionation Puzzle in Dissulfuribacter Thermophilus S69ᵀ Through Quantitative Label-Free Comparative Proteomics. [PDF]
Environ Microbiol RepTo date, only three microorganisms have been functionally characterised for sulfur disproportionation. Our work identifies a fourth example and provides novel proteomic insights into its underlying pathways. These findings advance our understanding of microbial sulfur catabolism and highlight the ecological role of D.
Fernandez M +8 more
europepmc +2 more sources
Cell surface differences within the genus Methanosarcina shape interactions with the extracellular environment [PDF]
Journal of BacteriologyMethanosarcina are metabolically versatile methanogenic archaea that can perform extracellular electron transfer (EET), with important ecological and biotechnological implications.
Amelia-Elena Rotaru +4 more
doaj +2 more sources
Nanosecond heme-to-heme electron transfer rates in a multiheme cytochrome nanowire reported by a spectrally unique His/Met-ligated heme [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 2021 Stephen R. Meech +2 more
exaly +2 more sources
Large-scale prediction of outer-membrane multiheme cytochromes uncovers hidden diversity of electroactive bacteria and underlying pathways [PDF]
Frontiers in MicrobiologyMulti-heme cytochromes (MHCs), together with accessory proteins like porins and periplasmic cytochromes, enable microbes to transport electrons between the cytoplasmic membrane and extracellular substrates (e.g., minerals, electrodes, other cells ...
Arkadiy I. Garber +2 more
doaj +2 more sources
Discovery of a functional, contracted heme-binding motif within a multiheme cytochrome [PDF]
Journal of Biological Chemistry, 2019 Christina Ferousi +2 more
exaly +2 more sources
Nonuniform Distance Decay of Conductance in a Series of Multiheme Cytochrome Bioelectronic Junctions. [PDF]
J Phys Chem LettMultiheme cytochromes have emerged as a promising new class of bioelectronic materials for potential use in soft and biocompatible electronics. To aid these developments it is essential to understand how conductance decays with increasing size of ...
Pethő AM, Futera Z, Blumberger J.
europepmc +2 more sources
Frontiers in Microbiology, 2022 Exoelectrogenic microorganisms are in the spotlight due to their unique respiratory mechanisms and potential applications in distinct biotechnological fields, including bioremediation, bioenergy production and microbial electrosynthesis.
Jorge M. A. Antunes +7 more
doaj +1 more source