Results 71 to 80 of about 21,285 (307)

Territorial variation in mortality from causes amenable to medical care in Poland

open access: yesAnnals of Agricultural and Environmental Medicine, 2017
Introduction and objective This study examines the geographical variation of amenable mortality in Poland, focusing primarily on the role of health care resources at the level of administrative districts and regions, and selected area socioeconomic ...
Wiktoria Wróblewska
doaj   +1 more source

Magnetic Micro‐ and Nanorobots for Precision Thrombolysis: Design Strategies and Translational Challenges

open access: yesAdvanced Robotics Research, EarlyView.
Micro‐ and nanorobots for targeted thrombolysis. This perspective elaborates on the clinical indication of blood clot disorders and current limitations for treatment. As a novel, alternative solution, micro‐ and nanorobots can be used to treat and break down thrombi.
Joshua M. Mesfin   +3 more
wiley   +1 more source

Multilevel modelling of refusal and noncontact nonresponse in household surveys: evidence from six UK government surveys

open access: yes, 2007
This paper analyses household unit nonresponse and interviewer effects in six major UK government surveys using a multilevel multinomial modelling approach. The models are guided by current conceptual frameworks and theories of survey participation.
Durrant, Gabriele B., Steele, Fiona
core  

Spatial scale and the geography of tobacco smoking in New Zealand: a multilevel perspective

open access: yes, 2003
Smoking in New Zealand is more common in deprived areas and in areas with a significant Maori population. Despite its status as a major health problem there has been little work investigating this apparent geography of smoking.
Moon, Graham, Barnett, Ross
core   +1 more source

An On‐Demand Neuromorphic Vision System Enabled by a Multi‐Paradigm Neuromorphic Device and Hierarchical Reconfigurability Designed from Device to System Level

open access: yesAdvanced Science, EarlyView.
An on‐demand ultra‐reconfigurable intelligent vision system with hierarchical reconfigurability from device to system levels is demonstrated. Through co‐design of a multi‐paradigm device, reconfigurable circuits, and adaptive system architecture/algorithms, the system enables seamless switching among spiking, non‐spiking, neuromorphic imaging (NI), and
Biyi Jiang   +7 more
wiley   +1 more source

Full‐Body AI Agent: A Perspective on Multi‐Scale Collaborative AI for Systemic Biology and Precision Medicine

open access: yesAdvanced Science, EarlyView.
We propose the Full‐Body AI Agent, a multi‐scale collaborative framework with 7 biological‐layer agents. It unifies multi‐omics/clinical data via standardized protocols, enabling phenotype‐guided closed‐loop reasoning, quantitative evaluation, and LLM safeguards, with promising applications in tumor metastasis modeling and precision drug development ...
Aoqi Wang   +11 more
wiley   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

open access: yesAdvanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu   +7 more
wiley   +1 more source

S100A14 in Tumor‐Derived EVs Targets PIAS3 to Reprogram Astrocytes and Induce Immunosuppressive Microenvironment Promoting Brain Metastasis and Germacrone Reversal Effect

open access: yesAdvanced Science, EarlyView.
This study identifies S100A14 in tumor‐derived exosomes as a key driver of brain metastasis. S100A14 targets PIAS3 in astrocytes, activating STAT3 signaling and promoting immunosuppressive MDSCs recruitment via chemokine secretion. Germacrone, a natural compound, binds S100A14 to disrupt this axis, effectively inhibiting brain metastasis with low ...
Qian Feng   +13 more
wiley   +1 more source

Low, medium, and high-performing schools in the Nordic countries. Student performance at PISA Mathematics 2003-2012

open access: yesEducation Inquiry, 2020
Decreasing performance in several core subjects among students in Sweden and the increasing segregation of schools are urgent issues in relation to equity in education, which has been a long-term goal in Sweden.
Inga Laukaityte, Ewa Rolfsman
doaj   +1 more source

Module 8: Multilevel modelling in practice: Research questions, data preparation and analysis

open access: yes, 2010
In this module we consider the whole process of conducting a research project using multilevel modelling, taking as an example a study of ethnic differences in educational achievement and progress.
Fielding, Antony
core  

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