Results 41 to 50 of about 81,986 (300)

Clinical Course and Impact of Breaks in Therapy for Children With Relapsed/Refractory Solid Tumors

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Pediatric relapsed or refractory (R/R) solid tumors carry a dismal prognosis, and postrelapse patient experiences are not well described. We present postrelapse outcomes, including number of R/R events and subsequent therapy regimens.
Matthew T. McEvoy   +5 more
wiley   +1 more source

Alveolar Soft Part Sarcoma in Pediatric and Young Adult Patients: A Report From the Children's Oncology Group Study ARST0332

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Alveolar soft part sarcoma (ASPS) is a rare soft tissue sarcoma occurring most commonly in adolescence and young adulthood. Methods We present the clinical characteristics, treatments, and outcomes of patients with newly diagnosed ASPS enrolled on the Children's Oncology Group study ARST0332.
Jacquelyn N. Crane   +11 more
wiley   +1 more source

Generation of multi-modal dialogue for a net environment [PDF]

open access: yes, 2002
In this paper an architecture and special purpose markup language for simulated affective face-to-face communication is presented. In systems based on this architecture, users will be able to watch embodied conversational agents interact with each other ...
Baumann, S.   +8 more
core  

Digital interaction: where are we going? [PDF]

open access: yes, 2018
In the framework of the AVI 2018 Conference, the interuniversity center ECONA has organized a thematic workshop on "Digital Interaction: where are we going?".
Amendola, Massimo   +17 more
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

ELAN-based multimodal discourse analysis of the interactive meanings and persuasive methods in criminal trials

open access: yesLanguage and Semiotic Studies
Courtroom interaction is a distinct form of communication. It entails verbal and visual resources and abilities to express meaning, negotiate, and, hence, persuade.
Zaiton Hoda
doaj   +1 more source

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

EXPERIMENTAL METHODS OF EXPLORING MULTIMODAL DISCOURSE: CROSSMODAL ALIGNMENT

open access: yesВестник Волгоградского государственного университета: Серия 2. Языкознание
The study advances Crossmodal Alignment Framework to explore multimodal discourse in its three formats – semiotic, communicative and perceptive – via multimodal experiment.
Mariya I. Kiose   +2 more
doaj   +1 more source

Multimodal Discourse on BRICS Produced by Diverse Stakeholders: Identifying Attitudes, Cultures and Perspectives

open access: yesSpace and Culture, India, 2020
The paper explores the conceptual vision of BRICS in the contemporary world. The study focuses on language and images that are used within BRICS-related institutional communication. We argue that the research is important because of the increasing impact
Anastasia Atabekova   +2 more
doaj   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

open access: yesFEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig   +7 more
wiley   +1 more source

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