Results 21 to 30 of about 266,006 (205)

Mass spectrometry imaging identifies altered hepatic lipid signatures during experimental Leishmania donovani infection

Frontiers in Immunology, 2022
IntroductionSpatial analysis of lipids in inflammatory microenvironments is key to understand the pathogenesis of infectious disease. Granulomatous inflammation is a hallmark of leishmaniasis and changes in host and parasite lipid metabolism have been ...
Roel Tans, Shoumit Dey, Nidhi Sharma Dey, Jian-Hua Cao, Prasanjit S. Paul, Grant Calder, Peter O’Toole, Paul M. Kaye, Ron M. A. Heeren   +8 more
doaj   +1 more source

Structural Analysis of the Partially Disordered Protein EspK from Mycobacterium Tuberculosis

Crystals, 2020
For centuries, tuberculosis has been a worldwide burden for human health, and gaps in our understanding of its pathogenesis have hampered the development of new treatments.
Abril Gijsbers, Nuria Sánchez-Puig, Ye Gao, Peter J. Peters, Raimond B. G. Ravelli, Dritan Siliqi   +5 more
doaj   +1 more source

Feasibility and safety of non-contrast optical coherence tomography imaging using hydroxyethyl starch in coronary arteries

Scientific Reports, 2023
Intracoronary optical coherence tomography (OCT) requires injection of flushing media for image acquisition. Alternative flushing media needs to be investigated to reduce the risk of contrast-induced renal dysfunction. We investigated the feasibility and
Dong Oh Kang, Hyeong Soo Nam, Sunwon Kim, Hongki Yoo, Jin Won Kim   +4 more
doaj   +1 more source

Targeted theranostic photoactivation on atherosclerosis

Journal of Nanobiotechnology, 2021
Background Photoactivation targeting macrophages has emerged as a therapeutic strategy for atherosclerosis, but limited targetable ability of photosensitizers to the lesions hinders its applications.
Joon Woo Song, Jae Won Ahn, Min Woo Lee, Hyun Jung Kim, Dong Oh Kang, Ryeong Hyun Kim, Un Gyo Kang, Yeon Hoon Kim, Jeongmoo Han, Ye Hee Park, Hyeong Soo Nam, Hongki Yoo, Kyeongsoon Park, Jin Won Kim   +13 more
doaj   +1 more source

Hemodynamic correlates of fluctuations in neuronal excitability: A simultaneous Paired Associative Stimulation (PAS) and functional near infra-red spectroscopy (fNIRS) study

NeuroImage: Reports, 2022
Background: The relationship between task-related hemodynamic activity and brain excitability is poorly understood in humans as it is technically challenging to combine simultaneously non-invasive brain stimulation and neuroimaging modalities.
Zhengchen Cai, Giovanni Pellegrino, Amanda Spilkin, Edouard Delaire, Makoto Uji, Chifaou Abdallah, Jean-Marc Lina, Shirley Fecteau, Christophe Grova   +8 more
doaj   +1 more source

Imaging markers of disability in aquaporin-4 immunoglobulin G seropositive neuromyelitis optica: a graph theory study [PDF]

, 2019
Neuromyelitis optica spectrum disorders lack imaging biomarkers associated with disease course and supporting prognosis. This complex and heterogeneous set of disorders affects many regions of the central nervous system, including the spinal cord and ...
Asseyer, Susanna, Bellmann-Strobl, Judith, Brandt, Alexander U., Chien, Claudia, Kuchling, Joseph, Oertel, Frederike Cosima, Paul, Friedemann, Ruprecht, Klemens, Scheel, Michael, Siebert, Nadja, Zimmermann, Hanna   +10 more
core   +2 more sources

Mass spectrometry imaging of L-[ring-13C6]-labeled phenylalanine and tyrosine kinetics in non-small cell lung carcinoma

Cancer & Metabolism, 2021
Background Metabolic reprogramming is a common phenomenon in tumorigenesis and tumor progression. Amino acids are important mediators in cancer metabolism, and their kinetics in tumor tissue are far from being understood completely.
Jianhua Cao, Benjamin Balluff, Martijn Arts, Ludwig J. Dubois, Luc J. C. van Loon, Tilman M. Hackeng, Hans M. H. van Eijk, Gert Eijkel, Lara R. Heij, Zita Soons, Steven W. M. Olde Damink, Ron M. A. Heeren   +11 more
doaj   +1 more source

Groupwise Multimodal Image Registration using Joint Total Variation [PDF]

, 2020
In medical imaging it is common practice to acquire a wide range of modalities (MRI, CT, PET, etc.), to highlight different structures or pathologies.
A Collignon, A Myronenko, A Roche, AV Cideciyan, C Studholme, C Wachinger, C Wu, DL Hill, DN Greve, E Haber, F Maes, FP Oliveira, G Sapiro, J Ashburner, J Huang, J Orchard, JBA Maintz, JP Lewis, JP Pluim, JV Hajnal, M Brudfors, M Polfliet, P Blomgren, P Gerlot-Chiron, P Snape, P Viola, RP Woods, RP Woods, WH Press, WM Wells III, X Bresson, ZS Saad, Ž Spiclin   +32 more
core   +2 more sources

Adversarial Deformation Regularization for Training Image Registration Neural Networks [PDF]

, 2018
We describe an adversarial learning approach to constrain convolutional neural network training for image registration, replacing heuristic smoothness measures of displacement fields often used in these tasks.
Barratt, Dean C., Bonmati, Ester, Emberton, Mark, Ghavami, Nooshin, Gibson, Eli, Hu, Yipeng, Moore, Caroline M., Noble, J. Alison, Vercauteren, Tom   +8 more
core   +2 more sources

Lipid Analysis of Fracture Hematoma With MALDI-MSI: Specific Lipids are Associated to Bone Fracture Healing Over Time

Frontiers in Chemistry, 2022
Background: Fracture healing is a complex process, involving cell-cell interactions, various cytokines, and growth factors. Although fracture treatment improved over the last decades, a substantial part of all fractures shows delayed or absent healing ...
Rald V. M. Groven, Rald V. M. Groven, Sylvia P. Nauta, Sylvia P. Nauta, Jane Gruisen, Jane Gruisen, Britt S. R. Claes, Johannes Greven, Martijn van Griensven, Martijn Poeze, Martijn Poeze, Ron M. A. Heeren, Tiffany Porta Siegel, Berta Cillero-Pastor, Taco J. Blokhuis, Taco J. Blokhuis   +15 more
doaj   +1 more source