Results 31 to 40 of about 138,615 (266)

Multimodality Imaging of Prostate Cancer [PDF]

Journal of Nuclear Medicine, 2019
Prostate cancer is a very heterogeneous disease, and contemporary management is focused on identification and treatment of the prognostically adverse high-risk tumors while minimizing overtreatment of indolent, low-risk tumors. In recent years, imaging has gained increasing importance in the detection, staging, posttreatment assessment, and detection ...
Ghafoor, Soleen, Burger, Irene A, Vargas, Alberto H   +2 more
openaire   +3 more sources

Spatial differentiation of metabolism in prostate cancer tissue by MALDI-TOF MSI

Cancer & Metabolism, 2021
Background Prostate cancer tissues are inherently heterogeneous, which presents a challenge for metabolic profiling using traditional bulk analysis methods that produce an averaged profile.
Maria K. Andersen, Therese S. Høiem, Britt S. R. Claes, Benjamin Balluff, Marta Martin-Lorenzo, Elin Richardsen, Sebastian Krossa, Helena Bertilsson, Ron M. A. Heeren, Morten B. Rye, Guro F. Giskeødegård, Tone F. Bathen, May-Britt Tessem   +12 more
doaj   +1 more source

SARS-CoV-2–Specific Vaccine Candidates; the Contribution of Structural Vaccinology

Vaccines, 2022
SARS-CoV-2 vaccine production has taken us by storm. We aim to fill in the history of concepts and the work of pioneers and provide a framework of strategies employing structural vaccinology.
Su Min Pack, Peter J. Peters
doaj   +1 more source

Approaches to Multimodality Imaging of Angiogenesis [PDF]

Journal of Nuclear Medicine, 2010
Angiogenesis, defined as the formation of new capillaries by cellular outgrowth from existing microvessels, can be assessed by the evaluation of perfusion, function, and metabolism. However, more recently, novel, noninvasive imaging strategies for the evaluation of molecular events associated with the angiogenic process have been developed.
Dobrucki, Lawrence W., de Muinck, Ebo D., Lindner, Jonathan R., Sinusas, Albert J.   +3 more
openaire   +4 more sources

Multimodal Imaging and Hybrid Scanners [PDF]

International Journal of Biomedical Imaging, 2007
There is an old tale of three blind men who were brought to the zoo for the first time and allowed to touch the elephant. On their way home, they shared this exciting experience. “An elephant is a long, flexible, and cylindrical creature,” said the man who had touched the elephant's trunk. “No!
Haim Azhari, Robert R. Edelman, David W. Townsend   +2 more
openaire   +3 more sources

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

In situ and in vitro cryo-EM reveal structures of mycobacterial encapsulin assembly intermediates

Communications Biology
Prokaryotes rely on proteinaceous compartments such as encapsulin to isolate harmful reactions. Encapsulin are widely expressed by bacteria, including the Mycobacteriaceae, which include the human pathogens Mycobacterium tuberculosis and Mycobacterium ...
Casper Berger, Chris Lewis, Ye Gao, Kèvin Knoops, Carmen López-Iglesias, Peter J. Peters, Raimond B. G. Ravelli   +6 more
doaj   +1 more source

ABCDscores: an R package for computing summary scores in the ABCD Study®

Frontiers in Neuroinformatics
The ABCD Study® is the largest longitudinal research study of brain development and child health across the United States. The study generates a rich multimodal dataset, including file-based raw and derivative data and a curated tabulated dataset ...
Le Zhang, Olivier Celhay, Biplabendu Das, Samantha Berman, Laura R. Ziemer, Calen J. Smith, Shermaine Abad, Anders M. Dale, Janosch Linkersdörfer   +8 more
doaj   +1 more source

Central Nervous System Neuroblastoma, FOXR2‐Activated: A Pooled Analysis of Published Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) neuroblastoma, FOXR2‐activated, is a recently recognized entity in the WHO CNS5 classification, defined by activation of the FOXR2 transcription factor and unique histopathological features. This review synthesizes available literature and pooled clinical data, providing insight into demographics ...
Sudarshawn Damodharan, Mohamed S. Abdelbaki   +1 more
wiley   +1 more source

Multimodal precision MRI of the individual human brain at ultra-high fields

Scientific Data
Multimodal neuroimaging, in particular magnetic resonance imaging (MRI), allows for non-invasive examination of human brain structure and function across multiple scales.
Donna Gift Cabalo, Ilana Ruth Leppert, Risavarshni Thevakumaran, Jordan DeKraker, Youngeun Hwang, Jessica Royer, Valeria Kebets, Shahin Tavakol, Yezhou Wang, Yigu Zhou, Oualid Benkarim, Nicole Eichert, Casey Paquola, Julien Doyon, Christine Lucas Tardif, David Rudko, Jonathan Smallwood, Raul Rodriguez-Cruces, Boris C. Bernhardt   +18 more
doaj   +1 more source