Results 31 to 40 of about 157,902 (299)

Original Research. Transluminal Contrast Attenuation Gradient Is Associated with Coronary Plaque Vulnerability — a Computed Tomography Angiography-based Study

Journal of Cardiovascular Emergencies, 2017
The aim of this study was to demonstrate that the transluminal contrast attenuation gradient (TAG), a new CT imaging-derived marker of functional significance of a coronary stenosis, is directly associated with the vulnerability degree of atheromatous ...
Orzan Marius, Hodas Roxana, Dobra Mihaela, Rat Nora, Chitu Monica, Benedek Imre   +5 more
doaj   +1 more source

Approaches to Multimodality Imaging of Angiogenesis [PDF]

Journal of Nuclear Medicine, 2010
Angiogenesis, defined as the formation of new capillaries by cellular outgrowth from existing microvessels, can be assessed by the evaluation of perfusion, function, and metabolism. However, more recently, novel, noninvasive imaging strategies for the evaluation of molecular events associated with the angiogenic process have been developed.
Dobrucki, Lawrence W., de Muinck, Ebo D., Lindner, Jonathan R., Sinusas, Albert J.   +3 more
openaire   +4 more sources

Spatial differentiation of metabolism in prostate cancer tissue by MALDI-TOF MSI

Cancer & Metabolism, 2021
Background Prostate cancer tissues are inherently heterogeneous, which presents a challenge for metabolic profiling using traditional bulk analysis methods that produce an averaged profile.
Maria K. Andersen, Therese S. Høiem, Britt S. R. Claes, Benjamin Balluff, Marta Martin-Lorenzo, Elin Richardsen, Sebastian Krossa, Helena Bertilsson, Ron M. A. Heeren, Morten B. Rye, Guro F. Giskeødegård, Tone F. Bathen, May-Britt Tessem   +12 more
doaj   +1 more source

SARS-CoV-2–Specific Vaccine Candidates; the Contribution of Structural Vaccinology

Vaccines, 2022
SARS-CoV-2 vaccine production has taken us by storm. We aim to fill in the history of concepts and the work of pioneers and provide a framework of strategies employing structural vaccinology.
Su Min Pack, Peter J. Peters
doaj   +1 more source

Multimodal Imaging and Hybrid Scanners [PDF]

International Journal of Biomedical Imaging, 2007
There is an old tale of three blind men who were brought to the zoo for the first time and allowed to touch the elephant. On their way home, they shared this exciting experience. “An elephant is a long, flexible, and cylindrical creature,” said the man who had touched the elephant's trunk. “No!
Haim Azhari, Robert R. Edelman, David W. Townsend   +2 more
openaire   +3 more sources

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

In situ and in vitro cryo-EM reveal structures of mycobacterial encapsulin assembly intermediates

Communications Biology
Prokaryotes rely on proteinaceous compartments such as encapsulin to isolate harmful reactions. Encapsulin are widely expressed by bacteria, including the Mycobacteriaceae, which include the human pathogens Mycobacterium tuberculosis and Mycobacterium ...
Casper Berger, Chris Lewis, Ye Gao, Kèvin Knoops, Carmen López-Iglesias, Peter J. Peters, Raimond B. G. Ravelli   +6 more
doaj   +1 more source

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman, Katherine K. Matthay, Fabienne Hollinger, Catriona Black, Ann A. Lazar, Miguel Pampaloni, Steven G. DuBois, Kieuhoa T. Vo   +7 more
wiley   +1 more source

Multimodal precision MRI of the individual human brain at ultra-high fields

Scientific Data
Multimodal neuroimaging, in particular magnetic resonance imaging (MRI), allows for non-invasive examination of human brain structure and function across multiple scales.
Donna Gift Cabalo, Ilana Ruth Leppert, Risavarshni Thevakumaran, Jordan DeKraker, Youngeun Hwang, Jessica Royer, Valeria Kebets, Shahin Tavakol, Yezhou Wang, Yigu Zhou, Oualid Benkarim, Nicole Eichert, Casey Paquola, Julien Doyon, Christine Lucas Tardif, David Rudko, Jonathan Smallwood, Raul Rodriguez-Cruces, Boris C. Bernhardt   +18 more
doaj   +1 more source

Flexible endoscopic micro-optical coherence tomography for three-dimensional imaging of the arterial microstructure

Scientific Reports, 2020
Micro-optical coherence tomography (µOCT) is a novel imaging approach enabling visualization of the microstructures of biological tissues at a cellular or sub-cellular level.
Junyoung Kim, Sunwon Kim, Joon Woo Song, Hyun Jung Kim, Min Woo Lee, Jeongmoo Han, Jin Won Kim, Hongki Yoo   +7 more
doaj   +1 more source