Causal association of cognitive reserve on Alzheimer's disease with putative sex difference
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 2021 Introduction Sex‐dependent risk factors may underlie sex differences in Alzheimer's disease (AD). Methods Using sex‐stratified genome‐wide association studies (GWAS) of AD, we evaluated associations of 12 traits with AD through polygenic risk scores (PRS)
Hao Wang +8 more
doaj +1 more source
Personalized Pancreatic Tumor Growth Prediction via Group Learning
, 2017 Tumor growth prediction, a highly challenging task, has long been viewed as a mathematical modeling problem, where the tumor growth pattern is personalized based on imaging and clinical data of a target patient. Though mathematical models yield promising
C Hogea +7 more
core +1 more source
A holistic multimodal approach to the non-invasive analysis of watercolour paintings [PDF]
, 2015 A holistic approach using non-invasive multimodal imaging and spectroscopic techniques to study the materials (pigments, drawing materials and paper) and painting techniques of watercolour paintings is presented.
Bailey, K +6 more
core +2 more sources
Contracted functional connectivity profiles in autism
Molecular AutismObjective Autism spectrum disorder (ASD) is a neurodevelopmental condition that is associated with atypical brain network organization, with prior work suggesting differential connectivity alterations with respect to functional connection length.
Clara F. Weber +13 more
doaj +1 more source
Distinctive Mechanisms and Patterns of Exudative Versus Tractional Intraretinal Cystoid Spaces as Seen With Multimodal Imaging. [PDF]
, 2020 PurposeTo determine clear-cut distinctions between tractional and exudative intraretinal cystoid spaces subtypes.DesignRetrospective, multicenter, observational case series.MethodsA cohort of patients diagnosed with intraretinal cystoid spaces and imaged
Au, Adrian +9 more
core
Measuring cortical connectivity in Alzheimer's disease as a brain neural network pathology: Toward clinical applications [PDF]
, 2016 Objectives: The objective was to review the literature on diffusion tensor imaging as well as resting-state functional magnetic resonance imaging and electroencephalography (EEG) to unveil neuroanatomical and neurophysiological substrates of Alzheimer ...
BABILONI, CLAUDIO +6 more
core +1 more source
Similar Genetic Architecture of Alzheimer’s Disease and Differential APOE Effect Between Sexes
Frontiers in Aging Neuroscience, 2021 Sex differences have been observed in the clinical manifestations of Alzheimer’s disease (AD) and elucidating their genetic basis is an active research topic.
Hao Wang +9 more
doaj +1 more source
Image Synthesis in Multi-Contrast MRI with Conditional Generative Adversarial Networks
, 2018 Acquiring images of the same anatomy with multiple different contrasts increases the diversity of diagnostic information available in an MR exam. Yet, scan time limitations may prohibit acquisition of certain contrasts, and images for some contrast may ...
Dar, Salman Ul Hassan +5 more
core +2 more sources
Colon adenocarcinoma diagnosis in human samples by multicontrast nonlinear optical microscopy of hematoxylin and eosin stained histological sections [PDF]
, 2014 Combined multimodal nonlinear optical (NLO) microscopies were used to detect and quantify morphological changes associated with stroma and epithelial transformation in colon cancer.
Adur, Javier Fernando +7 more
core +1 more source
Atypical functional connectome hierarchy in autism
Nature Communications, 2019 Autism spectrum disorder (ASD) is associated with symptoms ranging from sensory hypersensitivity to social difficulties. Here, the authors provide evidence of atypical connectivity transitions between sensory and higher-order cortical areas in people ...
Seok-Jun Hong +10 more
doaj +1 more source