Results 61 to 70 of about 132,432 (269)

Epigenetic regulation of histone modifications in glioblastoma: recent advances and therapeutic insights

Biomarker Research
Glioblastoma (GBM) is the most common primary malignant brain tumor, characterized by its aggressive behavior, limited treatment options, and poor prognosis. Despite advances in surgery, radiotherapy, and chemotherapy, the median survival of GBM patients
Li Zhang, Yang Yang, Yanchu Li, Chenyu Wang, Chenbin Bian, Hongbin Wang, Feng Wang   +6 more
doaj   +1 more source

Multimodality of rich clusters from the SDSS DR8 within the supercluster-void network

, 2012
We study the relations between the multimodality of galaxy clusters drawn from the SDSS DR8 and the environment where they reside. As cluster environment we consider the global luminosity density field, supercluster membership, and supercluster ...
A. Ahvensalmi, Aihara, Andrade-Santos, Araya-Melo, Bardelli, Belsole, Bird, Blanton, Blanton, Boschin, Bourdin, Burgett, Clarke, de Lapparent, E. Saar, E. Tago, E. Tempel, Einasto, Einasto, Einasto, Einasto, Einasto, Einasto, Einasto, Einasto, Einasto, Einasto, Einasto, Einasto, Einasto, Einasto, Einasto, Einasto, Espino-Briones, Fakhouri, Flin, Fraley, Gastaldello, Hahn, Haines, Hoffman, Hou, Huchra, Ihaka, J. Einasto, J. Vennik, Jeeson-Daniel, Jõeveer, Knebe, Kolokotronis, Kopylova, Kopylova, L. J. Liivamägi, Liivamägi, Loeb, Lubin, M. Einasto, M. Gramann, Markevitch, Martínez, McIntosh, Mo, Noh, Oort, Owers, P. Heinämäki, P. Nurmi, Padilla-Torres, Park, Pinkney, Plionis, Pompei, Porter, Power, Pratt, Ragone-Figueroa, Richstone, Rose, Saar, Sahni, Schirmer, Shandarin, Sheth, Skibba, Small, Smith, Solanes, Suhhonenko, Tago, Tago, Tempel, Tempel, Tempel, Turner, V. J. Martínez, Wang, White, Wolf, Zeldovich   +98 more
core   +1 more source

A Coupled Oscillator Model for the Origin of Bimodality and Multimodality

, 2020
Perhaps because of the elegance of the central limit theorem, it is often assumed that distributions in nature will approach singly-peaked, unimodal shapes reminiscent of the Gaussian normal distribution.
Abrams, Daniel M., Johnson, Joseph D.
core   +1 more source

Prediction of Myasthenia Gravis Worsening: A Machine Learning Algorithm Using Wearables and Patient‐Reported Measures

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare disorder characterized by fluctuating muscle weakness with potential life‐threatening crises. Timely interventions may be delayed by limited access to care and fragmented documentation. Our objective was to develop predictive algorithms for MG deterioration using multimodal telemedicine data ...
Maike Stein, Haoqi Sun, Sophie Lehnerer, Lea Gerischer, Maximilian Mönch, Christian Meisel, Andreas Meisel, Pushpa Narayanaswami   +7 more
wiley   +1 more source

The value of multimodality imaging for detection, characterisation and management of a wall adhering structure in the right atrium [PDF]

, 2014
The case presents a wall adherent structure in the right atrium in a young patient with peripheral tcell lymphoma followed by successful prolonged lysis therapy resulting in the resolution of the thrombus is presented.
Akin, Ibrahim, Baumann, Stefan, Becher, Tobias, Behnes, Michael, Boecker, C., Borggrefe, Martin, Frambach, Daniel, Huseynov, Aydin, Papavassiliu, Theano, Rapp, S.   +9 more
core   +1 more source

Reduced Muscular Carnosine in Proximal Myotonic Myopathy—A Pilot 1H‐MRS Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Myotonic dystrophy type 2 (proximal myotonic myopathy, PROMM) is a progressive multisystem disorder with muscular symptoms (proximal weakness, pain, myotonia) and systemic manifestations such as diabetes mellitus, cataracts, and cardiac arrhythmias.
Alexander Gussew, Maryam Kargaran, Maik Rothe, Andreas Deistung, Dietrich Stoevesandt, Walter A. Wohlgemuth, David Strube, Thomas Kendzierski, Anna Katharina Kölsch, Maurits Gerhard Abraham Heuschen, Markus Otto, Alexander Mensch   +11 more
wiley   +1 more source

Acoustic Measures Capture Speech Dysfunction in Spinocerebellar Ataxia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxias (SCA) are hereditary cerebellar degenerative disorders with a common feature of dysarthria, involving impaired phonatory and articulatory control of speech, thereby affecting social communication. In this study, we investigated whether acoustic measures could objectively measure speech dysfunction and identify
Zena Fadel, Charlotte Hennessey, Hannah Lee, Pia Parekh, Sheng‐Han Kuo, Ami Kumar   +5 more
wiley   +1 more source

Clinical update. Computed Tomography — an Emerging Tool for Triple Rule-Out in the Emergency Department. A Review

Journal of Cardiovascular Emergencies, 2017
New imaging tools have been developed in recent years to rapidly and accurately diagnose life-threatening diseases associated with high mortality rates, such as acute coronary syndromes, acute aortic dissection, or pulmonary embolism.
Dobra Mihaela, Bordi Lehel, Nyulas Tiberiu, Stănescu Alexandra, Morariu Mirabela, Condrea Sebastian, Benedek Theodora   +6 more
doaj   +1 more source

Epicardial Fat Volume as a New Imaging-Based Feature Associated with Risk of Recurrence after Pulmonary Veins Ablation in Atrial Fibrillation

Journal of Interdisciplinary Medicine, 2020
Background: Atrial fibrillation (AF), a common arrhythmia in clinical practice, is associated with a high rate of complications and an increased risk for thromboembolic events.
Blîndu Emanuel, Korodi Szilamér, Bordi Lehel, Kovács István, Benedek Imre   +4 more
doaj   +1 more source

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani, Lakshmi Pillai, Reid D. Landes, Aliyah Glover, Shannon Doerhoff, Jennifer Kleiner, Mitesh Lotia, Rohit Dhall, Edgar Garcia‐Rill   +8 more
wiley   +1 more source