Results 31 to 40 of about 84,209 (281)

Multimorbidity and Evidence Generation [PDF]

Journal of General Internal Medicine, 2014
Most people with a chronic disease actually have more than one, a condition known as multimorbidity. Despite this, the evidence base to prevent adverse disease outcomes has taken a disease-specific approach. Drawing on a conference, Improving Guidelines for Multimorbid Patients, the goal of this paper is to identify challenges to the generation of ...
Weiss, Carlos O, Varadhan, Ravi, Puhan, Milo A, Vickers, Andrew, Bandeen-Roche, Karen, Boyd, Cynthia M, Kent, David M   +6 more
openaire   +2 more sources

Health-related preferences of older patients with multimorbidity: the protocol for an evidence map [PDF]

, 2019
Introduction: Interaction of conditions and treatments, complicated care needs and substantial treatment burden make patient–physician encounters involving multimorbid older patients highly complex.
Blom, Jeanet, Gerlach, Ferdinand M, González-González, Ana Isabel, Hoffmann, Tammy, Meerpohl, Joerg J, Muth, Christiane, Nguyen, Truc Sophia, Nothacker, Julia, Röttger, Kristian, Schmucker, Christine, Straus, Sharon E, van den Akker, Marjan, Wegwarth, Odette   +12 more
core   +1 more source

Prevalence of common chronic disease and multimorbidity patterns in Guangdong province with three typical cultures: analysis of data from the Diverse Life-Course Cohort study

Frontiers in Public Health, 2023
BackgroundVariations in the prevalence and pattern of multimorbidity might be attributable to lifestyle and environmental factors. This study was performed to determine the prevalence of common chronic diseases and to reveal multimorbidity patterns among
Yaoda Hu, Huijing He, Qiong Ou, Jing Nai, Li Pan, Xingming Chen, Ji Tu, Xuejun Zeng, Guo Pei, Longlong Wang, Binbin Lin, Qihang Liu, Guangliang Shan   +12 more
doaj   +1 more source

Comment on: “GLM7 – A Novel Composite Glycolipid Index Derived from Routine Health Indicators for Enhanced Diagnosis and Prediction of Multimorbidity”

Advanced Science, EarlyView.
ABSTRACT The recent study by Wang et al. introduces GLM7, a novel composite index integrating routine health indicators to enhance the diagnosis and prediction of multimorbidity. The study provides compelling evidence for the utility of cost‐effective biomarkers in large‐scale health screening.
Yiquan Wang, Tin‐Yeh Huang
wiley   +2 more sources

Regional variation in multimorbidity prevalence in British Columbia, Canada: a cross-sectional analysis of Canadian Community Health Survey data, 2015/16

Health Promotion and Chronic Disease Prevention in Canada, 2020
Introduction: Multimorbidity represents a major concern for population health and service delivery planners. Information about the population prevalence (absolute numbers and proportions) of multimorbidity among regional health service delivery ...
C. Andrew Basham
doaj   +1 more source

Oxygen Concentration Plays a Critical Role in Fibrinogen-Mediated Platelet Activation via Inactivation of α_IIbβ₃ and Modulation of Fibrinogen

Biomolecules
In the vascular system, pathological conditions that cause hypoxia are associated with increased platelet activity and thrombosis. Using a platelet spreading assay, we show that severe hypoxia (i.e., 1%), venous (i.e., 5%), and, surprisingly, arterial (i.
Sophie V. L. Leonard, Zoe Booth, Leigh Naylor-Adamson, Lewis Bibby, Katie S. Wraith, Giordano Pula, Monica Arman, Simon D. J. Calaminus   +7 more
doaj   +1 more source

Socioeconomic determinants of multimorbidity: a population-based household survey of Hong Kong Chinese [PDF]

, 2015
<b>Introduction</b> Multimorbidity has been well researched in terms of consequences and healthcare implications. Nevertheless, its risk factors and determinants, especially in the Asian context, remain understudied.
Chung, Roger Y., Lai, Francisco T.T., Mercer, Stewart, Wong, Martin C.S., Wong, Samuel Y.S., Yip, Benjamin H.K.   +5 more
core   +4 more sources

Enhancing research quality and reporting: why the Journal of Comorbidity is now publishing study protocols [PDF]

, 2014
The Journal of Comorbidity was launched in 2011 and has since become established as a high-quality journal that publishes open-access, peer-reviewed articles, with a focus on advancing the clinical management of patients with comorbidity/multimorbidity ...
Fortin, Martin, Gunn, Jane, Mercer, Stewart W., Smith, Susan M., van den Akker, Marjan   +4 more
core   +3 more sources

Formal and informal social care in people with Rheumatic and Musculoskeletal diseases: a cross‐sectional multicentre survey

Arthritis Care &Research, Accepted Article.
Introduction Rheumatic and musculoskeletal diseases(RMDs) are leading causes of physical disability, necessitating support with activities of daily living(ADLs). This study describes social care received by patients with RMDs in two disperate regions of England: Salford(urban) and Norfolk(rural).
Mehreen Somro, Karen Durrant, William G Dixon, John McBeth, Alex MacGregor, Max Yates, Jenny H Humphreys   +6 more
wiley   +1 more source

High‐Fidelity Synthetic Data Replicates Clinical Prediction Performance in a Million‐Patient Diabetes Cohort

Advanced Science, EarlyView.
This study generates high‐fidelity synthetic longitudinal records for a million‐patient diabetes cohort, successfully replicating clinical predictive performance. However, deeper analysis reveals algorithmic biases and trajectory inconsistencies that escape standard quality metrics. These findings challenge current validation norms, demonstrating why a
Francisco Ortuño, Víctor M. de la Oliva Roque, Javier‐Ignacio Ramirez‐Lopez, David P. Kreil, Joaquín Dopazo, Carlos Loucera   +5 more
wiley   +1 more source