ABSTRACT Objectives Retrograde trans‐synaptic degeneration (rTSD) from posterior visual pathway lesions in multiple sclerosis (MS) is characterized by hemi‐macular ganglion cell‐inner plexiform layer (GCIPL) thinning and contralateral visual field loss.
Abdul Jaber Tayem +17 more
wiley +1 more source
Distinguishing Molecular and Histologic Glioblastomas Using Multiparametric MRI-Based Habitat Analysis. [PDF]
Choi M +9 more
europepmc +1 more source
Dementia syndrome affects millions of people in the world, and Alzheimer's disease (AD) is the most common cause. We report the detection of the specific biomarker for AD, p‐tau‐181, from physiological to pathological concentrations in cerebrospinal fluid using an electrolyte‐gated organic transistor biosensor.
Marcello Berto +10 more
wiley +1 more source
Multiparametric MRI and artificial intelligence for non-invasive HER2 assessment in breast cancer: a comprehensive review. [PDF]
Zhang Y +5 more
europepmc +1 more source
Comparing diagnostic prostate cancer biomarkers using a framework of clinically meaningful criteria
Abstract Objectives To synthesize existing biomarker literature and generate a framework for meaningful comparison between five commonly used diagnostic prostate cancer biomarkers—prostate health index (phi), 4KScore, SelectMDx, ExoDx and MyProstate Score (MPS)—to provide evidence of greatest practical value to providers managing men with an elevated ...
Shu Wang +7 more
wiley +1 more source
Machine Learning with Multiparametric MRI and Clinical Biomarkers for Noninvasive Renal Interstitial Fibrosis Staging. [PDF]
Wang K +8 more
europepmc +1 more source
The use of biparametric magnetic resonance imaging in active surveillance of prostate cancer
Abstract Objectives This study aims to evaluate the performance of biparametric magnetic resonance imaging (bpMRI) compared to multiparametric MRI (mpMRI) for active surveillance (AS) in prostate cancer (PCa), focusing on lesion detection, PI‐RADS classification changes and grade reclassification (GR) rates.
Carlos A. Rivera López +9 more
wiley +1 more source
Calibrated and explainable multiparametric MRI radiomics for differentiating tumor positive disease from treatment-related changes in glioblastoma. [PDF]
Christodoulou RC +7 more
europepmc +1 more source
Glioblastoma (GBM) is a highly aggressive brain tumor with a poor prognosis, driven by abnormal signaling pathways that promote growth and resistance to treatment. Conventional therapies are inadequate, highlighting the need for novel multitargeted approaches.
Mehrukh Zehravi +13 more
wiley +1 more source
PSMA PET/CT-Targeted Biopsy in Men with Negative or Equivocal Multiparametric MRI and Exploratory Dynamic Total-Body PET: The FUPERMAN Study. [PDF]
Farolfi A +15 more
europepmc +1 more source

