Results 71 to 80 of about 12,192,482 (236)

Leximin Multiple Objective Optimization for Preferences of Agents

open access: yes, 2014
Gold Coast, QLD, Australia, 1-5 December ...
Toshihiro Matsui   +4 more
openaire   +3 more sources

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

open access: yesMolecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

open access: yesMolecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi   +2 more
wiley   +1 more source

Managerial multiple objective optimization [PDF]

open access: yesAnnals of Operations Research, 2018
Ralph E. Steuer   +2 more
openaire   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Multi-objective optimization techniques in electricity generation planning [PDF]

open access: yes, 2011
The objective of this research is to develop a framework of multi-objective optimization (MOO) models that are better capable of providing decision support on future long-term electricity generation planning (EGP), in the context of insufficient ...
Tuyiragize, Richard
core   +1 more source

Multi-Objective Optimization using Artificial Intelligence Techniques

open access: yes, 2020
This book focuses on the most well-regarded and recent nature-inspired algorithms capable of solving optimization problems with multiple objectives. Firstly, it provides preliminaries and essential definitions in multi-objective problems and different ...
Dong, Jin Song, Mirjalili, Seyedali
core   +1 more source

Knapsack Balancing via Multiobjectivization

open access: yesApplied Sciences
In this paper, we address the aspect of knapsack balancing in the classic knapsack problem. Recognizing that excessive dispersion in the objective function or constraint coefficients of the optimal solution can be undesirable, we propose, when ...
Ignacy Kaliszewski, Janusz Miroforidis
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

A Constrained Multi-Objective Optimization Algorithm with a Population State Discrimination Model

open access: yesMathematics
The solution to constrained multi-objective optimization problems (CMOPs) requires optimizing the objective functions while satisfying the constraint conditions. To effectively address CMOPs, algorithms must balance objectives and constraints.
Shaoyu Zhao   +3 more
doaj   +1 more source

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