Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Dual Generalized Nonnegative Normal Neutrosophic Bonferroni Mean Operators and Their Application in Multiple Attribute Decision Making [PDF]
Jiongmei Mo, Han-Liang Huang
openalex +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Multiattribute preference models with reference points [PDF]
In the context of multiple attribute decision making, preference models making use of reference points in an ordinal way have recently been introduced in the literature.
Denis Bouyssou, Thierry Marchant
core
Hamacher Operations for Complex Cubic q-Rung Orthopair Fuzzy Sets and Their Application to Multiple-Attribute Group Decision Making [PDF]
Qian Yu
openalex +1 more source
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Sistem Pendukung Keputusan Pemilihan Distribution Sales Supervisor dengan Metode FMADM-SAW pada PT. Nirmala Pangan Sejahtera Bekasi [PDF]
PT. Nirmala Pangan Sejahtera employ many marketing personnel to sell their products. While doing his job the marketing personnel is usually divided into several areas.
Mukhayaroh, A. (Anna)
core +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Issues of scale and scope in bio-physical modelling for natural resource management decision making in New South Wales [PDF]
Natural resource management decision making by Catchment Management Authorities in NSW is being aided by a project involving bio-physical modelling and the development of an alternative decision-making framework.
Farquharson, Robert J. +3 more
core +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source

