Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
An Approach to Linguistic Multiple Attribute Decision-Making Based on Unbalanced Linguistic Generalized Heronian Mean Aggregation Operator. [PDF]
Comput Intell Neurosci, 2018 Han B, Chen H, Zhu J, Liu J.
europepmc +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Intuitionistic Linguistic Multiple Attribute Decision-Making with Induced Aggregation Operator and Its Application to Low Carbon Supplier Selection. [PDF]
Int J Environ Res Public Health, 2017 Liu J, Wu X, Zeng S, Pan T.
europepmc +1 more source
FEBS Open Bio, EarlyView.This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
Intuitionistic linguistic weighted Bonferroni mean operator and its application to multiple attribute decision making. [PDF]
ScientificWorldJournal, 2014 Liu P, Rong L, Chu Y, Li Y.
europepmc +1 more source
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
Multiple goals in farmers’ decision making: The case of sheep farming in Western Greece [PDF]
Management strategies and performance differ among farmers, as a result of different, multiple and often conflicting goals. Many approaches to building farm level models that incorporate multiple goals have been developed over the years, most of which ...
Rozakis, Stelios +2 more
core +1 more source
Maximum Entropy-Minimum Residual Model: An Optimum Solution to Comprehensive Evaluation and Multiple Attribute Decision Making. [PDF]
Entropy (Basel)Tang QY, Lin YX.
europepmc +1 more source
Prioritizing the Determinants of Social-health Inequality in Iran: A Multiple Attribute Decision Making Application. [PDF]
Iran Red Crescent Med J, 2014 Zaboli R +3 more
europepmc +1 more source