Results 71 to 80 of about 9,891,766 (305)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Modelling and optimizing multiple attribute decisions by using fuzzy sets [PDF]
The purpose of this paper is to present a coherent perspective of modeling and optimizing multiple attribute decisions by using fuzzy sets. In management practice we face most of the time the situation in which a problem have several possible solutions ...
Adina NEGRUSA, Gh. Gh. IONESCU
core
Priority degrees for hesitant fuzzy sets: Application to multiple attribute decision making
Operations Research Perspectives, 2017 In this paper, some drawbacks to existing ordering relations for hesitant fuzzy sets are examined using examples. To overcome these flaws, a priority degree formula for comparing two hesitant fuzzy sets is presented and the desirable priority degree ...
Jibin Lan +3 more
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Multiple criteria decision making
, 1973 817 p., fig., ref. bib. : 17 p.1/2This volume is the direct result of a seminar on Multiple Criteria Decision Making held at the University of South Carolina on October 26-27, 1972. Support for this seminar and for production of this book was provided by
ZELENY, Milan, COCHRANE, James L.
core
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
FUZZY COMPARATIVE CONCORDANCE ANALYSIS. Proposal and evaluation by a case study [PDF]
In this paper it is proposed a fuzzy multiple attribute analysis, that we have called comparative concordance, as a help instrument to the decision-making process in an environment of lack of precise information as it generally is the decision-making in ...
Antonio Morillas +2 more
core
Neutrosophic Tangent Similarity Measure and Its Application to Multiple Attribute Decision Making [PDF]
Neutrosophic Sets and Systems, 2015 In this paper, the tangent similarity measure of neutrosophic sets is proposed and its properties are studied. The concept of this tangent similarity measure of single valued neutrosophic sets is a parallel tool of improved cosine similarity measure of ...
Kalyan Mondal, Surapati Pramanik
doaj
Dual hesitant pythagorean fuzzy Hamacher aggregation operators in multiple attribute decision making
Archives of Control Sciences, 2017 In this paper, we investigate the multiple attribute decision making (MADM) problem based on the Hamacher aggregation operators with dual Pythagorean hesitant fuzzy information.
Wei Guiwu, Lu Mao
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source