Results 71 to 80 of about 2,308,146 (271)

Assessment of need for capacity building in framing multiple choice questions for undergraduate medical students

Journal of the Scientific Society, 2016
Background: Assessment is a critical component of medical education because tests have a powerful influence on student learning. Multiple choice question (MCQ) tests have been established as a part of undergraduate and postgraduate medical education.
Sunil Kumar Raina, Mitasha Singh, Abhilash Sood, Vishav Chander   +3 more
doaj   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Evaluation of knowledge with multiple-choice tests: three of four options? Experience with admission examinations to medical and surgical postgraduate studies at University of Antioquia (Medellín, Colombia)

Iatreia, 2015
Introduction: The aim of this study was to evaluate the effect of reducing the number of response options per question on the psychometric indicators of an exam for admission to postgraduate medical studies, at University of Antioquia, in Medellín ...
Salazar Blanco, Olga Francisca, Vélez, Claudia Marcela, Zuleta Tobón, John Jairo   +2 more
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Assessment of Higher Ordered Thinking in Medical Education: Multiple Choice Questions and Modified Essay Questions

MedEdPublish, 2018
Background: Multiple choice questions and Modified Essay Questions are two widely used methods of assessment in medical education. There is a lack of substantial evidence whether both forms of questions can assess higher ordered thinking or not ...
Arslaan Javaeed
doaj  

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Using Multiple Choice Questions Written at Various Bloom's Taxonomy Levels to Evaluate Student Performance across a Therapeutics Sequence

INNOVATIONS in Pharmacy, 2011
Objective: To evaluate the results of a prospectively developed plan for using multiple choice questions (MCQs) developed at defined Bloom's levels to assess student performance across a Therapeutics sequence.
Amy M. Tiemeier, Zachary A. Stacy, John M. Burke   +2 more
doaj   +1 more source

Do Constructed-Response and Multiple-Choice Questions Measure the Same Thing? [PDF]

Our study empirically investigates the relationship between constructed-response (CR) and multiple-choice (MC) questions using a unique data set compiled from several years of university introductory economics classes.
Stephen Hickson, W. Robert Reed
core  

Introducing a framework to assess newly created questions with Natural Language Processing

, 2020
Statistical models such as those derived from Item Response Theory (IRT) enable the assessment of students on a specific subject, which can be useful for several purposes (e.g., learning path customization, drop-out prediction).
A Abyaa, CD Manning, GH Mc Laughlin, J Bergstra, J Verhagen, R Flesch, RC Atkinson, RK Hambleton, X Wang, Y Mao, Z Huang   +10 more
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source