Results 101 to 110 of about 1,773,114 (300)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Graphical comparisons of relative disease burden across multiple risk factors
BMC Medical Research Methodology, 2019 Background Population attributable fractions (PAF) measure the proportion of disease prevalence that would be avoided in a hypothetical population, similar to the population of interest, but where a particular risk factor is eliminated.
John Ferguson +4 more
doaj +1 more source
Toward a Theory of Nonparametric Multiple Comparisons [PDF]
, 1971 42 pages, 1 article*Toward a Theory of Nonparametric Multiple Comparisons* (Harner, E.
Harner, E. James +3 more
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FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Sisvar: a Guide for its Bootstrap procedures in multiple comparisons
Ciência e Agrotecnologia, 2014 Sisvar is a statistical analysis system with a large usage by the scientific community to produce statistical analyses and to produce scientific results and conclusions. The large use of the statistical procedures of Sisvar by the scientific community is
Daniel Furtado Ferreira
doaj +1 more source
Facts and Fictions About Handling Multiple Comparisons. [PDF]
J Grad Med Educ, 2021 Sullivan GM, Feinn RS.
europepmc +1 more source
Multiple Comparisons, Multiple Tests, and Data Dredging: A Bayesian Perspective [PDF]
, 1987 1 online resource (PDF, 23 pages)Berry, Donald A.. (1987). Multiple Comparisons, Multiple Tests, and Data Dredging: A Bayesian Perspective.
Berry, Donald A.
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Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Joint modeling and multiple comparisons with the best of data from a SMART with survival outcomes. [PDF]
Biostatistics, 2022 Chao YC, Tran Q, Tsodikov A, Kidwell KM.
europepmc +1 more source