Results 111 to 120 of about 1,773,114 (300)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Estimating the Proportion of True Null Hypotheses for Multiple Comparisons

Cancer Informatics, 2008
Whole genome microarray investigations (e.g. differential expression, differential methylation, ChIP-Chip) provide opportunities to test millions of features in a genome.
R.W. Doerge, Hongmei Jiang
doaj  

Multiple Comparisons for a Psychophysical Test in Bootstrap Logistic Regression

Journal of Algorithms & Computational Technology, 2014
We propose an algorithm of multiple comparisons with a control for a psychophysical test. Our algorithm is based on the step-down procedure and is applicable to the bootstrap test in logistic regression.
Norihiro Mita, Hiroshi Sasaki, Kazutaka Kani, Akio Tabuchi, Heihachiro Hara   +4 more
doaj   +1 more source

Reply to: Multiple Comparisons and Inappropriate Statistical Testing Lead to Spurious Sex Differences in Gene Expression. [PDF]

Biol Psychiatry, 2022
Walker DM, Cunningham AM, Nestler EJ.
europepmc   +1 more source

A comparative study on multiple comparisons procedures

, 2009
A comparative study on multiple comparisons procedures is performed and described, taking into account a new method to evaluate the performances af multiple comparisons procedures proposed by the ...
R. Arboretti Giancristofaro, Bonnini S., BONNINI, Stefano, ARBORETTI GIANCRISTOFARO, ROSA, F. Solmi, CORAIN, LIVIO, L. Corain, Solmi F.   +7 more
core  

A note on the use of multiple comparison scenario techniques in education and practice

, 2011
Our main aim in this paper is to highlight current practice and education in multiple scenario comparison within DES experimentation and to illustrate the possible benefits of employing false discovery rate (FDR) control as opposed to strict family-wise ...
Hoad, Kathryn, Thomas Monks, Monks, Thomas, Hoad, Kathryn A., Kathryn A. Hoad   +4 more
core   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Multiple Comparisons and Inappropriate Statistical Testing Lead to Spurious Sex Differences in Gene Expression. [PDF]

Biol Psychiatry, 2022
Mukamel EA.
europepmc   +1 more source

Bayesian Comparisons Between Representations [PDF]

peer reviewedWhich neural networks are similar is a fundamental question for both machine learning and neuroscience. Here, it is proposed to base comparisons on the predictive distributions of linear readouts from intermediate representations.
SCHÜTT, Heiko
core  

Effect of BG-12 on contrast-enhanced lesions in patients with relapsing-remitting multiple sclerosis: subgroup analyses from the phase 2b study

, 2011
Background: In a phase 2b study in patients with relapsing–remitting MS (RRMS), BG-12 240 mg three times daily significantly reduced the number of new gadolinium-enhanced (Gd+) lesions from weeks 12 to 24 (primary end point) by 69% compared with placebo.
Mefkure Eraksoy, Eraksoy, M., Eraksoy, Mefkure, O'Neill, G.N., Chris H Polman, Tarek A Yousry, Eva Meluzinova, Volker Limmroth, Minhua Yang, Havrdova, E., Gold, Ralf, Yang, Minhua, Limmroth, Volker, MacManus, D.G., Gilmore N O’Neill, Dufek, M., Meluzinova, E., Michal Dufek, Havrdova, Eva, Dawson, K., Schmierer, K., Miller, D. H., David G MacManus, Meluzinova, Eva, Polman, Chris H., Miller, David H., MacManus, David G., Ralf Gold, Schmierer, Klaus, Yousry, T.A., Ludwig Kappos, Yang, M.H., Yousry, Tarek A., O'Neill, Gilmore N., Eva Havrdova, Kappos, Ludwig, Polman, C.H., Klaus Schmierer, Kappos, L., Dufek, Michal, David H Miller, Limmroth, V., Dawson, Kate, Gold, R., Kate Dawson   +44 more
core   +1 more source