Results 41 to 50 of about 44,921 (261)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

COMPLEX VARIABLE FUNCTION SOLUTIONS OF STRESS INTENSITY FACTORS FOR MULTIPLE HOLE-EDGE CRACKS

open access: yesJixie qiangdu, 2020
The acceleration effect in the process of collinear hole-edge cracks propagation of aircraft fuselage skin structure is mainly manifested by the interaction of stress intensity factors between multiple fatigue cracks. A modified approximate superposition
ZHU QingYu, JIANG JueYi
doaj  

Experimental Studies into the Analysis Required for the Durability Assessment of 7075 and 6061 Cold Spray Repairs to Military Aircraft

open access: yesAerospace, 2020
This paper presents an experimental study into the analysis required for the durability assessment of 7075 and 6061 cold spray repairs to military aircraft.
Rhys Jones   +4 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Approximate determination of stress intensity factor for multiple surface cracks [PDF]

open access: yesFME Transactions, 2018
In this paper a versatile and easy to use approximate procedure was used for the estimation of mode I stress intensity factors in case of multiple surface cracks in a three dimensional elastic body, subjected to remote uniaxial tensile loading.
Kastratović Gordana   +3 more
doaj  

Multiple Cracking of Metallized Polyimide Kapton Films

open access: yesEurasian Chemico-Technological Journal, 2004
Mechanical behaviour of metallized polyimide Kapton films was studied. The adhesion of metallized films to Kapton films is approximately hundred-folds higher than that of coatings made by usual sputter deposition of a metal on a polymer substrate ...
S. L. Bazhenov   +5 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Dynamic analysis of extensible beam with multiple cracks

open access: yesJournal of Low Frequency Noise, Vibration and Active Control
We present the governing equation and study vibrations of multiple crack beams undergoing large deflections subject to transverse loads. First, the primary motion equation is derived using Hamilton’s principle applied to energy functions accounting for ...
Sudeok Shon, Junhong Ha, Semion Gutman
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

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