Results 61 to 70 of about 44,921 (261)
Fatigue properties and fracture mechanism of load carrying type fillet joints with one-sided welding
Fracture and Structural Integrity, 2015 The structures of the hydraulic excavator and the crane have numerous one-sided welded joints. However, attachments with box like structures are difficult to weld at both sides. Therefore, high accurate evaluation method is needed.
Takamasa Abe +3 more
doaj +2 more sources
An analysis of the interaction between surface and basal crevasses in ice shelves [PDF]
The CryosphereThe prescription of a simple and robust parameterization for calving is one of the most significant open problems in ice sheet modelling. One common approach to the modelling of crevasse propagation in calving in ice shelves is to view crevasse growth as
M. Zarrinderakht, C. Schoof, A. Peirce
doaj +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Nonplanar Crack Growth Simulation of Multiple Cracks Using Finite Element Method
Advances in Materials Science and Engineering, 2020 This work deals with a 2D finite element simulation of nonplanar multiple cracks using fracture and crack propagation analysis. This analysis was performed by using the developed source code software written by Visual Fortran Language.
Yahya Ali Fageehi +1 more
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
BuildingsIn engineering, concrete often develops cracks due to various reasons, which accelerate the erosion rate of chloride ions in concrete and consequently expedite the degradation of the mechanical properties of concrete structures. This study simplifies the
Tao Huang +3 more
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
A new adaptable multiple-crack detection algorithm in beam-like structures
Archives of Mechanics, 2013 In this article, a simple method for detecting, localizing and quantifying multiple cracks in beams using natural frequencies is presented. We model cracks as rotational springs and demonstrate a relationship among natural frequencies, crack locations ...
A. Ghadami, A. Maghsoodi, H.R. Mirdamadi
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source