Results 121 to 130 of about 2,277,621 (308)

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Positive multi-criteria models in agriculture for energy and environmental policy analysis [PDF]

open access: yes
Environmental consciousness and accompanying actions have been paralleled by the evolution of multi-criteria methods which have provided tools to assist policy makers in discovering compromises in order to muddle through.
Stelios Rozakis
core  

Analytic Hierarchy approach for transport project appraisal an application to Korea [PDF]

open access: yes, 1998
Transport evaluation methodology in Korea has remained largely unchanged even though the evolution of the transport planning process has changed in its nature and circumstances.
Lee , Sang Min
core  

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Multiple Criteria Games Theory and Applications

open access: yes, 1992
After a review of basic concepts in multiple criteria optimization, the paper presents a characterization of noncooperative equilibria in multiple criteria games in normal form either by weighted sums or by order-consistent achievement scalarizing ...
Wierzbicki, A.P.
core  

Analysis of the Next Evolution of Security Audit Criteria

open access: yes, 2023
Security assessments are performed for multiple reasons, including compliance with the information security regulation. Amongst other objectives, regulatory requirements are created to increase the resilience of national ...
Nykänen, Riku   +2 more
core  

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

A Multiple Criteria Framework to Evaluate Bank Branch Potential Attractiveness [PDF]

open access: yes
Remarkable progress has occurred over the years in the performance evaluation of bank branches. Even though financial measures are usually considered the most important in assessing branch viability, we posit that insufficient attention has been given to
Sérgio P. Santos   +3 more
core  

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

open access: yesFEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

A Multi-Criteria Decision Framework for Animal Welfare Policy

open access: yes
Policy decisions aimed at improving farm animal welfare involve balancing several competing objectives. Not only do such decisions involve tradeoffs between social, ethical, economic and welfare considerations, animal welfare itself is a multi ...
Hellstrom, J., Bicknell, Kathryn
core  

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