Results 111 to 120 of about 2,277,621 (308)
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
A Multiple Criteria Decision System to Improve Performance of Federal Conservation Programs
The Environmental Quality Incentives Program and other voluntary Federal conservation programs follow a similar approach for enrollment. Consistent with the legislation, agency personnel identify eligibility criteria, suitable conservation practices, and
Ozgoc-Caglar, C. Derya +1 more
core
Model Selection Criteria in Multivariate Models with Multiple Structural Changes [PDF]
This paper considers the issue of selecting the number of regressors and the number of structural breaks in multivariate regression models in the possible presence of mul- tiple structural changes.
Eiji Kurozumi, Purevdorj Tuvaandorj
core
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
A multiple criteria facility layout problem using data envelopment analysis [PDF]
In this paper, we propose a multi criteria decision making technique to determine an efficient solution for quadratic assignment problem. The proposed method of this paper considers transportation cost, adjacency and separation as the most important ...
Najmeh Bozorgi, Mostafa Abedzadeh
doaj
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Agribusiness, farm business and agricultural-environmental decisions which varied in their characteristics were used to evaluate multiple criteria decision making (MCDM) in an agricultural context.
Sheath, Gavin W. +2 more
core
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Social Multi-Criteria Evaluation (SMCE) [PDF]
The main argument developed here is the proposal of the concept of “Social Multi-Criteria Evaluation” (SMCE) as a possible useful framework for the application of social choice to the difficult policy problems of our Millennium, where, as stated by ...
Giuseppe Munda
core

